United States

Nanosized magnetic materials form a single domain and, as a result, magnetic nanoparticles (MNPs) usually lose their ferromagnetic properties. However,
superparamagnetic NPs can generate sufficient heat to kill cancer cells under a weak magnetic field. In this study, NiFe2O4 NPs with particle sizes of 3–17 nm were prepared for
application in magnetic hyperthermia treatment (MHT), and their biocompatibility was improved by modification with polyethylene glycol (PEG). PEG is hydrophilic and is often used in
the medical field. Direct current (DC) magnetization measurements showed that all the samples exhibited no hysteresis or superparamagnetic behavior at 300 K. The temperature
dependence of the alternating current (AC) magnetic susceptibilities revealed that the peak temperature of the imaginary part of AC magnetic susceptibilities (χ&quot;) varied significantly with
particle size, and the 17 nm sample had a peak at approximately 310 K. It is known that χ&quot; contributes significantly to heat generation owing to magnetic relaxation losses. The temperature
increase of the samples under an AC magnetic field (f = 15 kHz, h = 150 Oe) was measured. The sample with 17 nm particles showed a significant heating effect compared to the other
samples, reaching over 42.5 °C, which is sufficient to suppress cancer cells. Human breast cancer cells (MDA-MB-231) were cultured on a petri dish, and PEG-coated NiFe2O4 NPs were
added. The sample was heated using an AC magnetic field. Approximately 30% of cancer cells were successfully killed, and the magnetic hyperthermia effect was confirmed (Fig.1). To
evaluate the toxicity of PEG-coated magnetic NPs toward cancer cells, cell viability was observed for 24 h after the particles were dispersed in the culture dishes. PEG-coated NiFe2O4 NPs
successfully improved biocompatibility. Thus, NiFe2O4 NPs are expected to be useful agents for MHT. By using a zero-voltage switching (ZVS) circuit and generating an AC magnetic
field from a DC power source, a temperature rise two to eight times higher than that using conventional coils was achieved (Fig.2).&lt;br&gt;

**References:**&lt;br&gt;

P. Das, M. Colombo, D. Prosperi, Coll. Surf. B 174, 42 (2019)&lt;br&gt;

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MMM 2022

Biocompatible Superparamagnetic NiFe2O4 Nanoparticles for Magnetic Hyperthermia Treatment using a ZVS Circuit

Nanosized magnetic materials form a single domain and, as a result, magnetic nanoparticles (MNPs) usually lose their ferromagnetic properties. However,
superparamagnetic NPs can generate sufficient heat to kill cancer cells under a weak magnetic field. In this study, NiFe2O4 NPs with particle sizes of 3–17 nm were prepared for
application in magnetic hyperthermia treatment (MHT), and their biocompatibility was improved by modification with polyethylene glycol (PEG). PEG is hydrophilic and is often used in
the medical field. Direct current (DC) magnetization measurements showed that all the samples exhibited no hysteresis or superparamagnetic behavior at 300 K. The temperature
dependence of the alternating current (AC) magnetic susceptibilities revealed that the peak temperature of the imaginary part of AC magnetic susceptibilities (χ") varied significantly with
particle size, and the 17 nm sample had a peak at approximately 310 K. It is known that χ" contributes significantly to heat generation owing to magnetic relaxation losses. The temperature
increase of the samples under an AC magnetic field (f = 15 kHz, h = 150 Oe) was measured. The sample with 17 nm particles showed a significant heating effect compared to the other
samples, reaching over 42.5 °C, which is sufficient to suppress cancer cells. Human breast cancer cells (MDA-MB-231) were cultured on a petri dish, and PEG-coated NiFe2O4 NPs were
added. The sample was heated using an AC magnetic field. Approximately 30% of cancer cells were successfully killed, and the magnetic hyperthermia effect was confirmed (Fig.1). To
evaluate the toxicity of PEG-coated magnetic NPs toward cancer cells, cell viability was observed for 24 h after the particles were dispersed in the culture dishes. PEG-coated NiFe2O4 NPs
successfully improved biocompatibility. Thus, NiFe2O4 NPs are expected to be useful agents for MHT. By using a zero-voltage switching (ZVS) circuit and generating an AC magnetic
field from a DC power source, a temperature rise two to eight times higher than that using conventional coils was achieved (Fig.2). 

**References:** 

P. Das, M. Colombo, D. Prosperi, Coll. Surf. B 174, 42 (2019) 

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poster

#### Welcome to the 67th Annual Conference on Magnetism and Magnetic Materials, MMM 2022!

The Conference was held from October 31 to November 4 and offers both in-person and on-demand content.

MMM 2022 is sponsored jointly by AIP Publishing and the IEEE Magnetics Society. Members of the international scientific and engineering communities interested in recent developments in fundamental and applied magnetism are invited to attend and contribute to the technical sessions. The technical program will include invited and contributed papers in oral and poster sessions, invited symposia, a tutorial, and several special sessions. This Conference provides an outstanding opportunity for worldwide participants to meet their colleagues and collaborators and discuss developments in all areas of magnetism research.

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Please register for the MMM 2022 conference to join the event.

This Conference provides an outstanding opportunity for worldwide participants to meet their colleagues and collaborators and discuss developments in all areas of magnetism research.

This work describes the use of magnetoresistive (MR) sensors coupled with a portable platform for the detection of dengue virus (DENV), a mosquito-borne infection
endemic to low- and middle-income countries, affecting 100-400 million people each year[1]. Nowadays, diagnosis relies on molecular or serological tests. Still, these tests remain discrete
(RNA vs. antibodies), and tend to be complex and/or expensive, requiring expert staff and fully equipped laboratories. As such, this work aims to combine both assays in a single analysis
by simultaneously detecting DENV RNA and anti-DENV antibodies using a portable platform[2,3]. A spin-valve based biochip was designed and functionalized with specific DNA oligo
probes and secondary antibodies (Fig1A)[4]. Extracted RNA and serum samples were provided by INSA-CEVDI and used as targets in molecular and serological assays, respectively. In
both assays, streptavidin coated 250 nm magnetic nanoparticles were used for biolabeling. The measurement output is represented by a voltage drop (dV/V) proportional to the number of
captured target molecules (Fig1B). However, to increase the dynamic range of the assays, the percentage difference of dV/V signals obtained using different immobilization
strategies/probes, was taken as the final output signal. Using the MR-platform, individual tests were carried out for the detection of DENV RNA and anti-dengue human antibodies. The
RNA target was detected down to a few hundreds of pM (Fig2A). For the serological response, a calibration curve with an LOD of 1.38 nM was achieved. Infected patients’ serum was also
tested for anti-DENV antibodies, obtaining a sensitivity of 100% and a specificity of 92%(Fig2B). Finally, simultaneous detection of antibodies and RNA was successfully achieved on the
same chip, showing no differences to the individual assays. To increase the multiplexing capability of the assay, a biochip with 144 sensors and multi-level contact layers was developed
and is under testing using DENV as a model disease. This chip design will allow the simultaneous discrimination of various viruses endemic in the same regions. 

**References:** 

[1] Who.int. 2022. Dengue and severe dengue. [online] Available at: <https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue> [Accessed 14 June 2022]. 
[2] J. Germano et al., Sensors 9, 4119 (2009). 
[3] V. C. Martins et al., Biosensors and Bioelectronics 24, 2690 (2009). 
[4] D. C. Albuquerque et al., Biosensors and Bioelectronics 210, 114302 (2022). 

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Portable Magnetoresistive Device for the Simultaneous Detection of Dengue RNA and Anti dengue Antibodies

Currently, the treatment of suppression of cytokine storm in severe COVID-19 patients includes cytokine receptor suppression and depletion of specific immune cells in
addition to steroid treatment. Monoclonal antibody therapy is also one of the methods for depleting specific immune cells. It is a monoclonal antibody therapy against CD3, one of the
important signaling molecules for T-cell receptor activation. Among others, T cells secrete interferon gamma (IFN-γ), a pro-inflammatory cytokine responsible for inducing inflammation.
Therefore, monoclonal antibody therapy againstis a therapy that specifically depletes IFN-γ-secreting T cells. However, intravenous injection of an anti-CD3 monoclonal antibody targeting
all T cells induces significant immunosuppression and has side effects such as high fever and chills. The purpose of this study is to prepare an optimized liquid phase as a CD3 antibodymagnetic
nanoparticle (Ab-MNP) conjugate to inhibit the overactivation of T cells. In current study, we aimed to check distribution of Fe after acute admistration of silica-conjugated
amine nanoparticles delivered by intravenous injection. Besides, the IFN- γ levels in serum and spleen homogenates will be analyzed. Finally, we will develop film-type microneedle patch
using pulse-type magnetic stimulation to control the amount of liquid passing through the skin. The reason for choosing the spleen from the mouse organ is that it stores MNPs with a
particle size of 50 nm administered in vivo. Therefore, the result is a difference in the concentration of Fe elements, which was 1.89×103 mg/kg in the spleen of a control mouse not
administered with MNPs, whereas increases significantly to 1.93×103 mg/kg in that of a mouse administered with MNPs as shown in Fig. 1(a) and 1(b). IFN-γ level in spleen tissue and
serum is increased after 10 days. Further, time kinetic analysis of biochemical and immunological parameters are required to confirm its suitability in bio-administration. 

**References:** 

[1] N. S. Remya, S. Syama, A. Sabareeswaran, and P. V. Mohanan, Toxicity, toxicokinetics and biodistribution of dextran stabilized Iron oxide Nanoparticles for biomedical
applications, International Journal of Pharmaceutics 511, 586-598 (2016). 
[2] F. Gao, An Overview of Surface-Functionalized Magnetic Nanoparticles: Preparation and Application for Wastewater Treatment, Chemistry Select 4, 6805-6811 (2019).<br<
[3] R. Q. Cron, R. Caricchio, and W. W. Chatham, Calming the cytokine storm in COVID-19, Nature Medicine 27, 1674–1675 (2021). 
[4] C. Kuhn and H. L. Weiner, Therapeutic anti-CD3 monoclonal antibodies: from bench to bedside, Immunotherapy 8, 889–906 (2016). 

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Analysis of Fe element and interferon gamma in serum and spleen homogenates after injection of silica coated magnetic nanoparticles (SiO2 Fe3O4)

In this work, we have displayed an easy way to produce monodisperse spinel nanoparticles (NPs), as well as the antifungal activity of CoFe2O4, Co0.5Zn0.5Fe2O4 and
ZnFe2O4 nanostructures. Firstly, the structural, morphological and magnetic properties of each NP were fully investigated through x-ray diffraction (XRD), Transmission Electron
Microscopy (TEM) and Vibrating Sample Magnetometer (VSM). The XRD data showed diffraction peaks related to the crystalline spinel phase. No additional phase was observed, which
evidences the purity of the nanostructure synthesized. The TEM micrographs displayed monodisperse NPs with spherical morphology. The average sizes of CoFe2O4, Co0.5Zn0.5Fe2O4
and ZnFe2O4 NPs were found to be 6.87 ± 0.05 nm, 5.18 ± 0.01 nm and 11.52 ± 0.09 nm, respectively. The VSM data indicated the nanostructures are superparamagnetic at room
temperature. Afterwards, the antifungal properties of the Co/Zn-based ferrite NPs against Botrytis cinerea were tested. So, the inhibition of mycelial growth by different concentrations (45
– 360 ppm) of NPs was measured. The most effective nanostructure was found to be CoFe2O4 with an EC50 value of 265 ppm. To go further and elucidate how the NPs are affecting B.
cinerea, reactive oxygen species (ROS) production was measured. The results indicated that the CoFe2O4 monodisperse NPs are able to induce a burst of ROS in B. cinerea, promoting
damage cellular. 

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Easy synthesis of monodisperse Co/Zn based ferrite nanoparticles and their antifungal activities on Botrytis cinerea

Magnetic nanomaterials such as magnetite (Fe3O4) are sought after for their promising applications in sensing, drug delivery, tissue engineering and are also used as
contrast agents in magnetic resonance imaging [1 ].Synthesis of these nanomaterials with good uniformity in size and shape is imperative for their use in different applications.
Microfluidic-based synthesis in designed reactors is a new technology which controls the mixing of fluids within a fixed channel dimension (ranging from 10-100 μm), offers efficient mass
transport in channels and also reduces reaction time.[2,3] Herein, we present a new synthesis strategy which utilizes 3D-printing technique to develop a microfluidic device for synthesis of
Fe3O4 nanoparticles by droplet-based method.[4] The droplet-based method uses oil as a continuous medium which confines the reactants in a droplet, and each droplet functions as an
individual reactor thereby providing high level of control on synthesis conditions. This strategy overcomes the limitations of conventional glassware-based synthesis such as polydispersity
and batch-to-batch variability in nanoparticles. Enhanced magnetism and monodispersity in Fe3O4 nanoparticles were controlled by application of AC voltage across the electrodes placed
beneath the reaction chamber of the device. The present device can be used for synthesing metal nanoparticles. 

**References References:** 

1. A. H. Lu, E. Salabas, F. Schüth (2007) Magnetic nanoparticles: synthesis, protection, functionalization, and application. Angew. Chem. 119:1242-1266; Angew. Chem. Int. Ed. 46:
1222-1244 
2. G. M. Whitesides (2006) The origins and the future of microfluidics. Nature 442:368–373 
3. K. Ren, J. Zhou, H. Wu (2013) Materials for Microfluidic Chip Fabrication. Acc. Chem. Res. 46:2396–2406 
4. V. Singh, R. Singh (2022) Voltage-Driven Microfluidic Synthesis of Magnetite and Gold Nanomaterials. J Flow Chem. DOI: 10.1007/s41981-022-00231-3. 

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Simple Synthesis of Magnetic Nanomaterials by Microfluidics Process

Magnetic fluids have a unique combination of magnetic properties, fluidity and colloidal stability, which has allowed them to find applications in a variety of technical
devices, such as shock absorbers and sensors. One of the features of this smart material is the ability to control its physical properties using various combinations of magnetic influences. In
this work, the dynamics of a magnetic fluid volume levitating in an uniform magnetic field of an electromagnet undergoing oscillatory shear is investigated. The samples with different
physical parameters were considered, the dependence of magnetoviscous effect was investigated. It is shown that the microstructure of the sample and the presence of large magnetic
particles have the greatest influence on the dynamics of the magnetic fluid undergoing oscillatory shear and magnetoviscous effect. The results of the work can be used to develop a method
for express testing of magnetic fluid samples, as well as to develop acceleration and vibration sensors based on magnetic fluids [1].
The dependences of the viscosity for samples MF-1 – MF-4 are plotted, shown in Figure 1. The obtained dependences of the viscosity show an increase in its value by a factor of 5 for the
MF-1 sample, with an increase in the field to 1000 kA/m, which can be explained by interparticle interactions and the formation of weakly bound aggregates in the near-wall layer in a
more concentrated initial MF-1 sample. In a more diluted sample MF-2, such an increase in viscosity is not observed. The images MF-3, MF-4 are characterized by the presence of an
excess free surfactant, which negatively affects the magnetoviscous effect.
The work was carried out the part of the implementation of the program of strategic academic leadership "Priority-2030" (Agreements No. 075-15-2021-1155 and No. 075 -15-2021-1213)
and as part of the implementation of the state task (No 0851-2020-0035). 


**References:** 1. Ryapolov P. A., Polunin V. M., Shel'deshova E. V, JMMM 496, 165924 (2020). 

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Dynamics of magnetic fluids and bidisperse magnetic systems undergoing oscillatory shear

Various biomedical magnetic robots have been widely investigated as a possible means to replace conventional invasive regimens [1-3]. In our previous research, we
proposed a self-assembled magnetic millirobot with a multi-modular ring-like chain structure (SAMR) that can change its equilibrium formations under different conditions [4]. The SAMR
is composed of several arc-shaped modules serially connected by a pin joint, and a magnet is inserted into each module (Fig. 1). Due to the interactive magnetic forces and torques within
the modules, the SAMR can be self-assembled into a ring formation without a magnetic field or disassembled into a straight formation under an applied magnetic field. In this research, we
further investigated the wireless manipulation abilities of the SAMR’s mechanical motions. Based on the mechanical conditions of the SAMR shown in Fig. 1, we established a method that
can generate and maneuver the SAMR’s various mechanical movements, including self-assembly, disassembly, tumbling, crawling, and cargo trapping motions simply via the control of an
external magnetic field. Since such motions allow the low-invasive manipulation of the SAMR during the access to a target area and the performance of functions in the area, as shown in
Fig. 1, these motion abilities can significantly improve the SAMR’s usefulness as a minimally invasive device. In an experiment to verify the effectiveness of the proposed motion control
method, the SAMR initially disassembled and loaded inside the medical syringe successfully self-assembled into a ring formation. The SAMR then sequentially showed tumbling,
crawling, and cargo trapping and delivery motions actuated by different magnetic fields. This research can contribute to developing minimally invasive biomedical magnetic robots. 

**References** 

[1] M. Sitti, H. Ceylan, W. Hu, J. Giltinan, M. Turan, S. Yim, and E. Diller, “Biomedical Applications of Untethered Mobile Milli/Microrobots,” Proc. IEEE, vol. 103, no. 2,
pp. 205-224, 2015. 
[2] S. Yim and M. Sitti, “SoftCubes: Stretchable and self-assembling three-dimensional soft modular matter,” Int. J. Rob. Res., vol. 33, no. 8, pp. 1083–1097, 2014. 
[3] H. Lee and S. Jeon, “A Study on the Self-Assembly and Disassembly Abilities of a Multi- Modular Magnetic Millirobot,” J. Inst. Cont., Rob. Sys.,” vol. 25, no. 3, pp. 235-240, 2019. 
[4] H. Lee and S. Jeon, “An intravascular helical magnetic millirobot with a gripper mechanism performing object delivery and collecting motions actuated by precession rotating magnetic
fields,” AIP Adv., vol. 11, pp. 025236, 2021. 

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Wireless Manipulation of a Self Assembled Magnetic Millirobot with a Multi

An effective vibration isolator (VI) strategy isolates payloads from vibration sources by introducing compliance. Passive isolators are low cost and easy to install but are
tuned to a specific vibration spectrum, and rapidly lose effectiveness if the design point shifts. In contrast, adaptive vibration isolators using magnetorheological fluids (MRFs) continuously
adapt to changing vibration spectra by adjusting a magnetic field using an appropriate control algorithm. Traditional fabrication methods using injection molding are economical only when
large numbers are produced, which precludes customizing VIs for a specific available jitter space, natural frequency, or static displacement. 3D printing is advantageous for a
magnetorheological vibration isolator (MRVI) because designs can be customized: the shape of the hydraulic rubber reservoir can be economically customized to meet the requirements of
a specific application by tuning such properties as axial stiffness, bulge stiffness, diameter, height, and Shore hardness of the membrane wall. The MRVI, which is a squeeze-mode device,
consists of a reservoir or rubber bellow with customizable stiffnesses, a plastic lid which houses an electromagnetic coil, and an MRF (Figure 1). The rubber bellow and plastic lid were
fabricated using a Masked Stereolithography (MSLA) 3D printer. The electromagnet was mounted onto the lid, the reservoir was filled with an MRF, and the lid was twisted onto the
reservoir using a large thread. Using a testing machine, the damper forces of the 3D-printed MRVI were measured under constant velocity conditions for different magnetic fields. From
these tests, the magnetic field-controllable performances such as the dissipated energy and the dynamic force range of the MRVI were obtained (Figure 2). The feasibility of the 3D-printed
MRVI was experimentally confirmed. In addition, using 3D printing, and by selecting Shore hardness of the material, wall thickness, bellow shape, and MRF Fe particle volume fraction, a
broad range of VI applications can be addressed with this design methodology. 

**References:** 

1. S. Kaul, “Modeling and Analysis of Passive Vibration Isolation Systems,” Elsevier, 1st Ed., 2021, DOI: 10.1016/C2019-0-00013-1. 
2. M. Brigley, Y. T. Choi and N. M. Wereley, “Experimental and Theoretical Development of Multiple Fluid Mode Magnetorheological Isolators,” Journal of Guidance, Control, and
Dynamics, Vol. 31, No. 3, pp. 449-459, 2008, DOI: 10.2514/1.32969. 

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Design and Performance of A 3D Printed Magnetorheological Fluid

Magnetic hydrogels, or ferrogels, are smart materials that can mechanically deform in response to an applied magnetic field. Ferrogels possess potential applications in soft robotics, tissue engineering, artificial muscles, and controlled drug release due to their soft tissue-like state and biocompatibility potential. Hydrogels are a 3D hydrophilic polymer network linked by physical or chemical crosslinking, whereas ferrogels are a composite material that possess magnetic responsiveness due to the incorporation of a magnetic additive. Polyvinyl Alcohol (PVA) is unique among hydrogels due to the formation of physical crosslinks when subjected to cycles of freezing and thawing, enhancing mechanical properties without the use of a crosslinker that could compromise biocompatibility. The first aim of this work is to understand the differing effects of magnetically soft and hard additives on the magnetic, mechanical, and magnetoactive properties of PVA ferrogels by investigating PVA hydrogels impregnated with soft and hard magnetic particulate (magnetite (Fe3O4) and strontium ferrite (SrFe12O19), respectively). While magnetically hard polymer composites allow for more complex motion and actuation, soft magnetic additives often allow for greater response due to particle realignment when under a magnetic field. The next aim of this work studies the effects of magnetic annealing these ferrogels during crosslinking by comparing their resulting magnetic, mechanical, and magnetoactive properties with analogous control samples. Magnetoactive properties are determined by quantifying the angle of sample deflection in an applied transverse magnetic field, via a custom digital image overlay program. Scanning Electron Microscopy (SEM) is used to analyze the structural features of the hydrogel matrix and magnetic particulate. Results yield highly magnetoactive hydrogel samples with tunable responsiveness based upon magnetic particulate type, content, and presence of magnetic annealing. Figure 1 shows the magnetic responsiveness of ferrogels at varying magnetite contents.

Magnetoactive Properties of Biocompatible Magnetic Hydrogel Composites: Effects of Magnetic Particulate Type and Magnetic Annealing

Herewith, magnetic MOF composite material was utilized as an efficient adsorbent for direct red 81 (DR81) dye from wastewater. The synthesized magnetic MOF was
characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM), field emission transmission electron microscopy (FETEM), Fourier-transform infrared spectroscopy
(FTIR), thermal gravimetrical analysis (TGA), and Brunauer-Emmett-Teller (BET) surface area analysis. The adsorption profile of DR81 anionic dye onto the prepared magnetic MOF was
investigated with various processing parameters such as pH, contact time, and dosage. The optimum dosage from the fabricated magnetic MOF for decontamination of DR81 was 2.0 g L-1
at pH=7 after 30 min. The maximum Langmuir monolayer adsorption capacity of the DR81 decontamination via the synthesized magnetic MOF was recorded 67.35 mg/g. These promising
data confirmed the availability of the synthesized magnetic MOF composite as an excellent adsorbent material for the adsorption of DR81 from aqueous media.
Acknowledgment: This paper is based upon work supported by Science, Technology & Innovation Funding Authority (STDF) under grant (43565). 

**References:** 

Mona Ossman,(1),* Eslam Salama,(1) Ali Hamdy,(1) Hassan Shokry Hassan,(2) Marwa F. Elkady(2)
(1)City of Scientific Research and Technological Applications (SRTA-City), New Borg El-Arab City, Alexandria 21934, Egypt
(2)Egypt-Japan University of Science and Technology, New Borg El-Arab City, Alexandria 21934, Egypt
Correspondence should be addressed to Mona Ossman; mhr1410@hotmail.com

Magnetic MOF composite material for decontamination of direct red 81 from polluted water

High-precision 3D reconstruction of multiple magnetic targets aims to reconstruct the three-dimensional shape, position and magnetic susceptibility of magnetic targets
based on discrete and noisy magnetic anomaly measurement data. It is widely used in anti-submarine, unexploded ordnance detection, subway magnetic pipeline detection and so on [1].
Currently, the research on three-dimensional reconstruction of multiple magnetic targets is still in the primary stage. Similar magnetic inversion technology is mainly studied in geological
exploration, including morphological inversion and physical inversion. For morphological inversion, it needs to know the magnetic susceptibility in advance, which leads to some
limitations in the reconstruction of unknown magnetic targets. For the physical inversion, because of the error of magnetic data and the lack of prior information, the effect of traditional
physical inversion method is not satisfactory [2]. In order to solve this problem, this paper proposes a center weighting 3D imaging method based on normalized cross-correlation
coefficient. The method selects magnetic gradient tensor data as observation data, calculates its cross-correlation coefficient with each cuboid cells. This can reduce the interference caused
by magnetic measurement noise and errors of magnetic measurement parameters [3]. And visualize the results to obtain the preliminary distribution of magnetic target (Figure 1). Then, the
spatial distribution and center position of the magnetic target are used as prior information to constrain the inversion equation. This can reduce the degree of freedom of the inversion
equation and get the optimal solution of the reconstruction result. Our simulation and experimental results show that the proposed method can realize 3D reconstruction of several simple
magnetic targets with a higher degree of fidelity (Figure 2). 

**References:** 

[1] Y. Wang, I. I. Kolotov, D. V. Lukyanenko et al, Computational Mathematics and Mathematical Physics, Vol. 60, p. 1000–1007 (2020) 
[2] G. Yin, L. Zhang, Journal of Magnetism and Magnetic Materials, Vol. 482, p. 229–238 (2019) 
[3] Y. Li, J. Song, H. Xia et al, Journal of Applied Physics, Vol. 127,104701 (2020) 

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Biocompatible Superparamagnetic NiFe2O4 Nanoparticles for Magnetic Hyperthermia Treatment using a ZVS Circuit

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Portable Magnetoresistive Device for the Simultaneous Detection of Dengue RNA and Anti dengue Antibodies

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