Lecture image placeholder

Premium content

Access to this content requires a subscription. You must be a premium user to view this content.

Monthly subscription - $9.99Pay per view - $4.99Access through your institutionLogin with Underline account
Need help?
Contact us
Lecture placeholder background


MMM 2022

November 07, 2022

Minneapolis, United States

Magnetic Hyperthermia of AFe2O4 (A=Fe, Mn, Co) Nanoparticles Prepared by Co precipitation Method.

With 10 million deaths in 2020 cancer remains one of the most challenging diseases in contemporary medicine. Chemotherapy, surgery, and radiation therapy are commonly used to treat cancer. These treatments severely harm healthy tissues and succeed rarely in advance stages of disease. Recent studies indicate that magnetic hyperthermia, which involves targeted delivery of magnetic nanoparticles to tumor cells followed by localised remote heating of cancer tissues could revolutionise clinical practice in the treatment of cancer, either as standalone intervention or adjunct to radiotherapy and chemotherapy. Water dispersible magnetic nanoparticles (MNPs) of ferrites (AFe2O4; A=Fe, Mn, Co) are the promising candidates for magnetic hyperthermia due to their high chemical stability, biocompatibility, moderate magnetization and high specific absorption rates (SAR). In this article, we have evaluated magnetic hyperthermia efficiency of water based magnetic fluids of AFe2O4 nanoparticles. AFe2O4 nanoparticles were synthesized by chemical co-precipitation method. Nanoparticles were coated with a bilayer of oleic acid and dispersed in water. MNPs concentrations in magnetic fluids were 70 mg/mL for Fe3O4, 200 mg/mL for MnFe2O4 and 60 mg/mL for CoFe2O4. Structural and magnetic properties of MNPs were investigated by X-Ray diffraction (XRD) and vibrating sample magnetometer (VSM), respectively. XRD study revealed that AFe2O4 NPs exhibits cubic inverse spinel structure. Fe3O4 (Ms = 48 emu/g, Mr = 2.60 emu/g, Hc = 49 Oe), MnFe2O4 (Ms = 40 emu/g, Mr = 2.60 emu/g, Hc = 35 Oe) and CoFe2O4 (44 emu/g, Mr = 10.10 emu/g, Hc =440 Oe) NPs exhibits soft ferromagnetic behaviour. Magnetic hyperthermia measurements were performed as a function of magnetic field strength (2-10 mT) and field frequency (162-935.6 kHz) for 10 minutes. MNPs exhibits highest SAR values for 10 mT field strength at 935.6 kHz. Amongst the tested MNPs, Fe3O4 has the highest SAR value (27.35 W/g), followed by MnFe2O4 (1.91 W/g) and CoFe2O4 (0.94 W/g). Considering this, it is concluded that amongst the inverse spinel ferrite nanostructures AFe2O4 (A=Fe, Mn, Co), Fe3O4 nanoparticles are most suitable for magnetic fluid hyperthermia applications.

Next from MMM 2022

Structural, Magnetic and Magnetocaloric study of Cr doped Gd3Fe5 x CrxO12, (0.0 ≤ x ≤ 0.3)

Structural, Magnetic and Magnetocaloric study of Cr doped Gd3Fe5 x CrxO12, (0.0 ≤ x ≤ 0.3)

MMM 2022

Jolaikha Sultana

07 November 2022

Stay up to date with the latest Underline news!

Select topic of interest (you can select more than one)


  • All Lectures
  • For Librarians
  • Resource Center
  • Free Trial
Underline Science, Inc.
1216 Broadway, 2nd Floor, New York, NY 10001, USA

© 2023 Underline - All rights reserved