United States

Healthcare disparities in the United States lead to nearly $35 billion in excess health expenditures annually and can include increased risks of surgical complications and mortality among at-risk patients. However, these disparities have yet to be clearly elucidated within the field of orthopedic surgery. Moreover, minority populations receive poor trauma care and increased complications after spine surgical &amp; joint replacement surgeries. This study aims to highlight the current disparities in orthopedics and provide strategies to decrease these discrepancies to provide equitable medical care. To accomplish this, we conducted a systematic review of the clinical, functional, and quality of life measures in relation to healthcare disparities in the field of orthopedics. Using the recommendations outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), we screened studies in language, race, transportation, and orthopedic trauma coverage and extracted current data to synthesize strategies to reduce disparities. Preliminary analysis indicates lack of access to reliable and robust public transit infrastructure interrupts the continuity of care and produces worse health outcomes, specifically in Hispanic populations. Additionally, disparities based on language demonstrate a difference in the outcomes of their care. With regards to trauma coverage, uninsured and minority populations experienced more iatrogenic complications, had an increased risk of major adverse events, longer wait times, and lower chances of undergoing surgery resulting in more major adverse events. These results underscore the need for educational interventions to improve patient follow-up care in orthopedic settings.

AMA Research Challenge 2022

Current Strategies for Decreasing Disparities in Orthopaedic Care: A Systematic Review

The OWSD General Assembly and international conference will be held entirely online for the first time in OWSD's 28-year history, allowing as many of OWSD's 7600+ members to participate as possible.

The conference theme is 'Women, science and development', exploring three areas of relevance: 1) the importance of basic sciences for development; 2) the impact of applied sciences on development and 3) including sex and gender as variables in scientific research.


**Keynote speakers include:** 
* Fabiola Gianotti, Director-General of CERN; 
* Bina Agarwal, an internationally celebrated economist specializing in the political economy of gender, poverty and inequality; and 
* Angela Saini, award-winning author of Inferior: How Science Got Women Wrong and the New Research That’s Rewriting the Story, Superior: The Return of Race Science, and other books. 

OWSD members will present their own research in the three themes during poster sessions throughout the conference. In addition, members will also present their own scientific and personal responses to the COVID-19 pandemic. All members will also have the opportunity to take part in a workshop on increasing their visibility and impact as a scientist, with a session on using podcasts for storytelling by Joy Owango and Adelle Onyango of the Training Centre in Communication (TCC Africa), followed by a session on filmmaking for impact by Nicole Leghissa, OWSD video consultant.

The conference will include a handover of the previous OWSD Executive Board to the new members, elected in June-July 2021. On the last day of the conference (19 November), the OWSD Italy Country Network will be launched. **This will be an in-person event in Trieste.** Italian government representatives and donors are invited to attend. The Trieste event will be coordinated with similar in person events being held in OWSD countries throughout the developing world and streamed online. At least 2,000 OWSD members, women scientists from developing countries around the world, are expected to participate online in the General Assembly and conference.

 

**ABOUT THE PROGRAMME**

In order to approach the complex and wide-ranging challenges of the 2030 Agenda for Sustainable Development, societies around the world must access and harness all the talent and experience available to them. The concerns and perceptions of the greatest number of all possible actors and recipients must be considered in order that the most relevant issues and effective solutions are found. Women are considerably underrepresented as researchers in STEM subjects around the globe; according to UNESCO Institute of Statistics (UIS) data, in 2019 the global average percentage of women researchers was still below 30%. Yet women typically have first hand specialist knowledge of the day-to-day challenges diverse individuals face within communities, and can be key informers in the design and development of their solutions. Moreover, since women are most often the providers of informal community support, if they are not fully informed—and if solutions are developed without their consultation—it may be the case that products, services and solutions are not relevant or appropriate. Technological advances may mean improved machines on large farms, for example, potentially increasing food production, but since the key points of food insecurity in the world are on small-scale farms managed by women throughout the Global South, such capital investments will have little impact in the areas where food production is most critical—and where women’s knowledgeable implementation of appropriate innovative technologies could make the most difference.

 
 


**Keynote Speakers:**
* Fabiola Gianotti, Director-General of CERN; 
* Bina Agarwal, an internationally celebrated economist specializing in the political economy of gender, poverty and inequality; and 
* Angela Saini, award-winning author of Inferior: How Science Got Women Wrong and the New Research That’s Rewriting the Story, Superior: The Return of Race Science, and other books. 

**Eminent Guests:**
* Elena Bonetti, Italian Minister for Family and Equal Opportunities
* Maria Cristina Messa,	Italian Minister of Universities and Research
* Shamila Nair-Bedouelle,	Assistant Director General for Natural Sciences, UNESCO
* Maria Chiara Carrozza,	President, National Research Council of Italy
* Kerstin Jonsson Cisse,	Head of Unit for Globally Sustainable Economic Development, Sida - Sweden
* Naser Faruqui,	Director of Education and Science at IDRC - Canada
* Ylann Schemm,	Director, Elsevier Foundation
* Alberto Quadrio Curzio,	President Emeritus of the Italian Academy of Sciences and Humanities 
* Mohamed Hassan,	President, TWAS the World Academy of Sciences

**Chairs, panelists, interviewers and other speakers:**
Jennifer Thomson, Tonya Blowers, Rana Dajani, Shobhana Narasimhan, Joy Owango, Elizabeth Pollitzer, Kausila Timsina, Elizabeth Bandason, Susana Arrechea, Reinabelle Reyes, Dorine Odongo, Elizabeth Pollitzer, Adelle Onyango, Nicole Leghissa, Jana Rodriguez Hertz, Maryse Nkoua Ngavouka, Kate Shaw, Chao Mbogo, Prativa Pandey, Edna Patricia Matta-Camacho, Amira Shaheen, Wezi Nyambili, Ana Lucía Martinez Abarca, Mashura Shammi, Therese Umuhoza, Dionica Gamboa, Marian Nkansah, Babalola Olubukola Oluranti, Esi Awuah, Fortunate Farirai, Atya Kapley, Hasin Anupama Azhari, Huda Basaleem, Nashwa Eassa, Shymaa Enany, Kleinsy Bonilla, Patricia Castillo-Briceno, Fang Xin

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OWSD 6th GENERAL ASSEMBLY AND INTERNATIONAL CONFERENCE

The conference theme is 'Women, science and development', exploring three areas of relevance: the importance of basic sciences for development; the impact of applied sciences on development, and including sex and gender as variables in scientific research.

Healthcare disparities in the United States lead to nearly $35 billion in excess health expenditures annually and can include increased risks of surgical complications and mortality among at-risk patients. However, these disparities have yet to be clearly elucidated within the field of orthopedic surgery. Moreover, minority populations receive poor trauma care and increased complications after spine surgical & joint replacement surgeries. This study aims to highlight the current disparities in orthopedics and provide strategies to decrease these discrepancies to provide equitable medical care. To accomplish this, we conducted a systematic review of the clinical, functional, and quality of life measures in relation to healthcare disparities in the field of orthopedics. Using the recommendations outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), we screened studies in language, race, transportation, and orthopedic trauma coverage and extracted current data to synthesize strategies to reduce disparities. Preliminary analysis indicates lack of access to reliable and robust public transit infrastructure interrupts the continuity of care and produces worse health outcomes, specifically in Hispanic populations. Additionally, disparities based on language demonstrate a difference in the outcomes of their care. With regards to trauma coverage, uninsured and minority populations experienced more iatrogenic complications, had an increased risk of major adverse events, longer wait times, and lower chances of undergoing surgery resulting in more major adverse events. These results underscore the need for educational interventions to improve patient follow-up care in orthopedic settings.

poster

Welcome to the largest national, multi-specialty research event **featuring research from 750 medical students, residents and fellows, and international medical graduates.**


#### Event Details
The 2022 American Medical Association Research Challenge includes a poster symposium hall and a semifinals hall with the top scored research. Log in at any time throughout the event to:
* **View posters and presentations** on a variety of topics and specialties
* **Score posters in the semifinals** to help decide the top five finalists (AMA member exclusive opportunity)
* **Connect with participants** and provide feedback to help advance their research

At the conclusion of this event, the AMA will announce the top five finalists who will advance to the AMA Research Challenge finals, present their research to an elite panel of judges and compete to win a $10,000 grand prize sponsored by Laurel Road.
 

#### Attend Live Forums
**Oct. 20, 6 — 7 p.m. Central**
 **How to plan a career in academic medicine** 
 Learn how to plan a career in academic medicine and get your questions answered. [Access Here](https://underline.io/events/363/lounge)
 
 **Speakers**
![](https://assets.underline.io/uploads/markdown_image/1/image/d5adb133dfc58eb0a6d469e9cedcd5d4.jpg)
Ricardo Correa, MD, EdD
![](https://assets.underline.io/uploads/markdown_image/1/image/5f9437ab87861538bf02b9ca7c0d926e.jpg)
Stuart M. Greenstein, MD
![](https://assets.underline.io/uploads/markdown_image/1/image/05b1b637c99286d558c371f8e8b185ce.jpg)
Stephanie Strohbeen, MD
 
 **Oct. 22, 11 a.m. — Noon Central**
 **How to get published**
 Learn tips to get your research published and get your questions answered. [Access Here](https://underline.io/events/363/lounge)
 
 **Speakers**
![](https://assets.underline.io/uploads/markdown_image/1/image/8ce6235e957d31cb5e6f9097cc6f6972.jpg)
Jessica Li, MD/PhD Candidate
![](https://assets.underline.io/uploads/markdown_image/1/image/9950ef2e0237f54cb3d8280334d42491.jpg)
Charles Lopresto, DO

### Sponsor
AMA would like to thank Laurel Road for sponsoring a $10,000 grand prize for the winner of the AMA Research Challenge. Laurel Road is not involved in the judging or scoring process to select the winner. The winner will be announced on Dec. 7 during the AMA Research Challenge finals. Payment of the grand prize will be directly from Laurel Road. See the AMA Research Challenge Official Rules for terms and conditions.

![](https://assets.underline.io/uploads/markdown_image/1/image/611e331d4a0eba0920f240cfc04b4d77.png)

**There is no registration fee for this event! **

Register to explore research in a variety of topics. AMA members get exclusive access to score posters in the semifinals.

**Please use the link below to register for free if you have not already done so:**

https://www.ama-assn.org/about/events/ama-research-challenge

Registration Is Required

Welcome to the largest national, multi-specialty research event featuring research from 750 medical students, residents and fellows, and international medical graduates.


Background: Coronavirus (COVID-19) is transmissible via aerosolized particles (0.07-0.09μm). Healthcare workers are at risk when treating COVID+ patients; therefore, it is imperative to find ways to protect frontline staff. Patients who need emergency procedures or those that involve the aerodigestive tract may place staff at high risk of COVID transmission, as COVID status may not be known. Power drills operate at faster rpm and require irrigation in order to cool down the bone. This study investigated particle generation during maxillofacial trauma repairs using power and self-drilling techniques at different distances from the operating table during open reduction and internal fixation (ORIF). In doing so, we aim to find ways to mitigate the risk of contracting airborne diseases such as COVID-19. 

Methods: Two cadaveric specimens in a simulated operating room underwent ORIF of midface and mandible fractures via intraoral incisions as well as maxillomandibular fixation (MMF) using hybrid arch bars. For both simulated ZMC and parasymphyseal mandible fractures, ORIF was performed utilizing self-drilling screws and a power drill. Real-time aerosol concentration was measured throughout each procedure using 3 particle counters placed 0.45, 1.68, and 3.81 m (1.5, 5.5, and 12.5 feet, respectively) from the operative site.

Results: There was a significant decrease in particle concentration in all procedures at 1.68 m compared to 0.45 m (P < 0.001). At all three distances away from the operative site, there was significantly less aerosolized particle generation when using self-drilling techniques compared to power drilling for ORIF (P < 0.01).

Conclusion: Based on our study, self drilling techniques, unlike power drills, operate at lower rpm and do not require irrigation, therefore generating fewer particles and mitigating aerosol spread. Using self-drills and maintaining physical distancing protocols in the OR significantly reduce the number of aerosolized particles, which can decrease the risk of COVID-19 infection to the surgical team. While we have become more adept with the rise of multiple vaccines and more PPE, there is still uncertainty with the long term effects of COVID, and mitigation efforts are still critical. Furthermore, this and future studies will help us prepare for future pandemics and helping other at-risk populations, such as those at risk of tuberculosis.

Quantifying Aerosol Generation in Maxillofacial Trauma Repair Techniques

Background: Recent studies in large databases characterize child abuse and investigate the utility of clinical decision tools to detect physical abuse. This study characterizes risk factors preceding a diagnosis of physical abuse (NAT) in the pediatric trauma population to explore the potential of administrative databases in detecting physical abuse.
Methods: The Maryland Health Services Cost Review Commission (HSCRC) public-use data was queried for patients aged 0-19 to balance the number of patient records with the constraints of the database. Suspected physical abuse, confirmed physical abuse, and trauma were outcomes identified using ICD10 codes. Using logistic regression, odds ratios for each diagnostic code were identified unadjusted and adjusted for age, sex, race, ethnicity, year of encounter, and payer. Significance equals p<.05 after Bonferroni/Holm adjustment. Analysis was conducted in R (R Core Team, 2022).
Results: We identified 2,230 patients diagnosed with confirmed or suspected physical abuse totaling 10,546 encounters prior to NAT diagnosis. We identified 396,575 pediatric trauma patients totaling 606,146 encounters. The regression model comparing diagnostic codes of confirmed or suspected NAT with pediatric trauma yielded hundreds of statistically significant diagnostic codes. We report only the diagnoses with the highest frequency in the confirmed or suspected NAT population adjusted for demographic characteristics.
Conclusion: We identify known risk factors and findings associated with the child abuse population, such as racial disparities, psychiatric conditions, and congenital conditions. Several hundred statistically significant diagnoses were identified, demonstrating the limited immediate clinical utility of any single diagnostic code. We identified diagnostic codes such as cough, asthma, and visual pathologies that increase the odds of NAT but are poorly characterized in the literature. A large number of statistically significant diagnoses presents an opportunity to use machine learning in the child abuse population to assist clinicians in diagnosing and identifying NAT.

Identifying Risk Factors Preceding Non-Accidental Trauma Among Pediatric Trauma Patients in the HSCRC dataset

Socio-demographic Characteristics of Childhood Asthma and its Association With Substance Abuse – US Cross-Sectional Survey Study

Background: In Puerto Rico (PR), statistics of developmental disorders have not been published since 2017 when nearly 3,000 cases were documented. Since the beginning of the COVID-19 pandemic, there’s been a decrease in visits to pediatrician’s office for both preventive and urgent reasons. Moreover, in January 2020, a magnitude 6.4 earthquake devastated part of PR leading to further suspension of pediatrician's office. It is this concern for the loss of surveillance, screening and follow up amid these events and the lack of current statistic in PR, that there is a need to evaluate the prevalence of developmental delays (PDD) in this population. For such we established two objectives: (1) explore the yearly PDD in children admitted to the pediatric unit and (2) identify if there’s been a change in PDD during and after natural disaster and COVID-19 pandemic. Methods: This is a retrospective cross-sectional study. Electronic charts of 1,082 patients, ages 1-60 month, with no previous neurodevelopmental condition and who were admitted to the pediatric unit, during January 2017- December 2021 were reviewed. We obtained their sociodemographic data and the results from the domains of gross motor, fine motor, communication. personal-social and problem solving of the Ages and Stages Questionare-3 (ASQ-3). Results: Of the patients evaluated 56% were male and 44% females, with more than 2/3 of them below the poverty index. The mean age of evaluation was 21.4 month. A steadily increase yearly PDD was noted in all ASQ-3 domains. Statistical analysis showed significance in 3 out of the 5 domains with p-values <0.05. Conclusion: Our study shows steadily increasing PDD in at all areas of development in 2020-2021, correlating with the years of the events. The growing trend is statically significant when compared with previous years, which may be explained by the loss of follow up during this period. To our knowledge, this the only study evaluating how the mentioned events correlate with the normal development of Puerto Rican children. It also provides a recent statistic of patients with some form of developmental delay, suggesting that the current estimate in PR is far lower than the actual PDD.

Trends in Developmental Delays During a Natural Disaster and Covid-19 Pandemic.

Background: Stigma surrounding mental health issues can prevent members of the Asian Indian diaspora living in the United States (US) from seeking adequate medical attention. Asian Indian Americans (AIAs), like other immigrant groups in the US, face increased psychological distress from migration, acculturation pressures, and other social determinants that can adversely impact functioning and quality of life. We sought to determine if self-reported data regarding attitudes towards mental health issues and rates of access to mental healthcare among AIAs were unique when compared to other racial/ethnic groups within the US using the nationally representative 2015-2018 National Health Interview Surveys (NHIS).

Methods: This cross-sectional study included 111,065 adults aged 18-84 years old. The data were first stratified by race. Chi-square tests of independence were performed by survey question using Python 3.10 to assess how race/ethnicity correlated with self-reported symptoms, diagnoses, and treatments of anxiety and depression. The Wilcoxon rank-sums test was then performed to determine the uniqueness of AIA responses within the US population. 

Results: Among 111,065 participants, 45.2% of respondents were male, 54.8% were female, 80.0% were white, 12.4% were black/African American, 1.3% were Native American, 1.2% were Asian Indian, 4.3% were other Asian, and 0.7% were other/multiple races. Race correlated with severity, symptoms, and treatment of both anxiety and depression. AIAs were most likely to self-report “never” experiencing symptoms such as nervousness (94.7%, p=0.0039), hopelessness (91.4%, p=0.010), worthlessness (94.7%, p=0.0039), and avolition (80.6%, p=0.0039) as compared to all other racial/ethnic groups at the 0.05 level of significance. AIAs were also more likely to report not receiving treatment for anxiety (95.7%, p=0.049) or depression (97.3%, p=0.049) in 2018. 

Conclusion: These data quantitatively indicate AIAs are less likely to self-report symptoms of anxiety and depression, and are less likely to seek treatment for the same. Given the prevalence of stigma concerning mental health in many South Asian cultures, it is essential to further investigate the nuances of how AIAs understand and advocate for their mental wellbeing. Further study is required to assess the role of stigma, overall mental health literacy, and possible success of targeted intervention with the AIA population.

Comparing Self-Reported Mental Health Data in Asian Indian Americans to National Trends

Abstract Title: Learning How to Cope: Medical Student Burnout and its Effect Over Emotional Development

Background: The medical curriculum is stressful due to its expanding academic workload, new responsibilities, and rigorous standardized testing. Some students have effective coping strategies to manage these stressors, while others may engage in maladaptive strategies that can lead to burnout syndrome. This study explores factors which may influence the development of burnout in future physicians.

Methods: Data was collected from self-report questionnaires of 131 medical students at the University of Puerto Rico-School of Medicine. Questionnaires were administered through REDCap and included the Maslach Burnout Inventory as a measure of burnout and Coping Strategies Survey. The study was approved by the UPR Institutional Review Board as protocol B1750121. Descriptive analyses were used to determine prevalence of burnout and coping strategies. Spearman’s Rho correlations were calculated to evaluate relationships between the variables. All analysis were performed using SPSS.


Results: Family support (rho=0.215, p=0.013) and visiting the Wellness center (rho= 0.193, p=0.027) were positively correlated with professional efficacy (PE). A negative correlation was observed between social withdrawal (rho=-0.341, p<0.001) and PE. Decreased eating (rho=0.259, p=0.003), social withdrawal (rho=0.372, p<0.001), compulsive shopping (rho=0.338, p< 0.001) and energy drink use (rho=0.202, p=0.020) were positively correlated to burnout. Seeking professional mental health help was associated with higher burnout (rho=0.185, p=0.35)

Conclusion: Dysfunctional coping strategies were correlated to increased mean burnout scores. In contrast, a moderate-strong correlation was observed between functional coping strategies with increased levels of PE and lower burnout levels. These results facilitate identification and promotion of effective strategies to decrease burnout among UPR-SoM students. Even though results were compelling, burnout could have been underestimated, therefore future longitudinal studies with similar cohorts are necessary to further investigate actual causal relationships.

Learning How to Cope: Medical Student Burnout and its Effect Over Emotional Development

Background: 
Studies suggest that LGBTQ+ youth are at increased risk of engaging in substance use and misuse, including alcohol, tobacco, and illicit drugs. The COVID-19 pandemic forced many students to transition to a virtual learning environment in 2020 and early 2021, and the impacts of this have been purported to be detrimental. This study examines the prevalence of alcohol and substance use among lesbian, gay, and bisexual US high school students prior to the pandemic in 2019 compared to early 2021. We hope to identify possible factors which contribute to substance use in this population and provide direction for future studies. 
Methods
Results from the 2019 Youth Risk Behavior Survey (YRBS) and 2021 Adolescent Behavior and Experiences Survey (ABES) were used for this study. These two surveys provide important data regarding the prevalence of substance use high school students before and during the COVID-19 pandemic. We selected 15 questions concerning alcohol and substance use common to both surveys and isolated results for lesbian, gay, and bisexual students. We directly compared results from 2019 and 2021 and calculated the relative change from 2019. 
Results
We found a decrease in prevalence for all 15 alcohol and substance use-related questions from 2019 to 2021 among lesbian, gay, and bisexual students. The largest relative decreases included “Ever used cocaine” (73% decrease), “Ever used ecstasy” (69% decrease), and “Were offered, sold, or given an illegal drug on school property” (62% decrease). “Ever used inhalants” demonstrated the most modest decrease at 7.4%.
Conclusion
This data illustrates what appear to be substantial decreases in alcohol and substance use among lesbian, gay, and bisexual high school students from 2019 to 2021. These decreases have occurred in the context of the COVID-19 pandemic, and reported increases in mental health problems among this population. These results should prompt further research into how social interactions at school (or the lack thereof) of LGBTQ+ youth contribute to patterns of alcohol and substance use. By identifying such factors, we can recognize potential points of intervention.

Prevalence of Substance Use among Lesbian, Gay, and Bisexual High School Students in 2019 vs. 2021

Background: Medicare reimbursements are federally determined, while Medicaid reimbursements are determined by each state. More variable Medicaid reimbursements can create financial and administrative burdens that may prevent patients from receiving care.
Objective: To evaluate and characterize state variation in Medicaid and Medicare published reimbursement rates for the 20 most commonly ordered computed tomography (CT), magnetic resonance imaging (MRI), ultrasound (US) and radiograph (XR) studies. 
Methods: The 20 most commonly performed CT, MRI, US, and XR studies (80 studies) based on Medicare’s 2019 National Summary Data File were evaluated. The technical and professional components of reimbursements were analyzed. Paired t-tests were used to compare the average provider reimbursement rates, the CV of reimbursement rates, and the proportion of each total reimbursement rate accounted for by the professional component between Medicare and Medicaid.
Results: Medicare reimbursement variation (CV range: 0.07-0.08) was significantly lower than Medicaid reimbursement variation (CV range: 0.217-0.548) (P < 0.05 for all studies). For Medicaid, US had the lowest variation (CV= 0.280), then CT (CV= 0.328), XR (CV= 0.345) and MRI (CV= 0.398). Medicare dedicated a higher percentage to professional components than Medicaid for CT and MRI (P < 0.001); Medicaid proportionally paid greater professional component fees for XR (P = 0.002). Most reimbursement volatility was due to fluctuations in the technical rather than professional components. 
Discussion: Medicaid reimbursements for the most commonly ordered imaging studies were significantly more variable than Medicare reimbursements. This reimbursement variation may limit access to imaging care for certain populations.

State Variation of Medicaid Reimbursement Rates in the 20 most commonly ordered CT, MRI, Ultrasound and Radiograph Studies May Contribute to Geographic Healthcare Disparities

Background
The 2013 United States Preventive Services Task Force (USPSTF) lung cancer screening (LCS) guidelines were derived from clinical trials of predominantly White men, and lower rates of LCS eligibility have subsequently been found for Black and Hispanic adults. We evaluated whether the revised 2021 USPSTF criteria reduced inequities in LCS eligibility among a racially diverse sample of lung cancer patients. 

Methods
We conducted a retrospective chart review of patients at an urban safety net hospital diagnosed with a primary lung malignancy between 2015-2020. LCS eligibility was determined based on age, pack-years, and smoking status. For all patients and exclusively ever-smokers, χ2 tests were used to evaluate differences in LCS eligibility among demographic variables (race, sex, ethnicity, education level, insurance type) for both the 2013 and 2021 USPSTF criteria. Patients who were ineligible for LCS were categorized by respective reasons.

Results
Among 678 lung cancer patients (46% female, mean age 66 ± 10 years), 51% were White and 39% were Black. Using the 2013 guidelines, White patients (183 [57%]) would have been more likely to be eligible than Black (89 [37%]) and other-race patients (23 [35%]) (p<0.0001). Using the 2021 guidelines, White patients (220 [68%]) remained more likely to be eligible for LCS than Black (130 [54%]) and other-race patients (31 [48%]) (p=0.0002). The most common reason for ineligibility using the 2013 (183 [50%]) and 2021 (90 [33%]) guidelines was not meeting the pack-years threshold. We identified 88 never-smokers [White (23%), Black (47%)]. Among exclusively ever-smokers, there was no significant difference in eligibility by race under the 2021 criteria [White (73%), Black (65%), other-race (65%); (p=0.48)]. For both the 2013 and 2021 guidelines, sex, ethnicity, education level, and insurance type were not associated with differential screening eligibility among the entire study sample nor exclusively ever-smokers.

Conclusion
The 2021 USPSTF LCS guidelines may not be sufficient to eliminate racial inequities in LCS eligibility among patients who go on to be diagnosed with lung cancer. Differential rates of lung cancer among never-smokers may contribute to this inequity. Further research is needed to refine LCS guidelines, with particular consideration of non-smoking risk factors.

Black Race Remains Associated with Lower Eligiblity for Screening Using 2021 US Preventive Services Task Force Recommendations among Lung Cancer Patients at an Urban Safety Net Hospital

Previous studies have evaluated comorbidities and sociodemographic factors individually or by type but not comprehensively. This study aims to analyze the influence of a wide variety of factors in a single study to better understand the big picture of their effects on case-fatalities. This cross-sectional study used county-level comorbidities, social determinants of health such as income and race, measures of preventive healthcare, age, education level, average household size, population density, and political voting patterns were all evaluated on a national and regional basis. Analysis was performed through Generalized Additive Models and adjusted by the COVID-19 Community Vulnerability Index (CCVI). Effect estimates of COVID-19 fatality rates for risk factors such as comorbidities, sociodemographic factors and determinant of health. Factors associated with reducing COVID-19 fatality rates were mostly sociodemographic factors such as age, education and income, and preventive health measures. Obesity, minimal leisurely activity, binge drinking, and higher rates of individuals taking high blood pressure medication were associated with increased case fatality rate in a county. Political leaning influenced case case-fatality rates. Regional trends showed contrasting effects where larger household size was protective in the Midwest, yet harmful in Northeast. Notably, higher rates of respiratory comorbidities such as asthma and chronic obstructive pulmonary disease (COPD) diagnosis were associated with reduced case-fatality rates in the Northeast. Increased rates of chronic kidney disease (CKD) within counties were often the strongest predictor of increased case-fatality rates for several regions. Our findings highlight the importance of considering the full context when evaluating
contributing factors to case-fatality rates. The spectrum of factors identified in this study must be analyzed in the context of one another and not in isolation.


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