
Patricia Pelufo Silveira
McGill University
dopamine
genomics
gene expression
early life adversity
metabolic and psychiatric comorbidities
gene network
early adversity
2
presentations
1
number of views
SHORT BIO
Dr Silveira is a the scientific director of the Genomics and Epigenetics Pillar of the Ludmer Centre for Neuroinformatics & Mental Health, based at the Douglas Research Centre, and affiliated with the Department of Psychiatry at McGill University. A pediatrician and neuroscientist, Dr Silveira’s research focuses on how perinatal and early-childhood environments interact with individual differences in biological processes, shaping and modulating both health and disease risk across the lifespan, into old age. Her aim is to identify how gene networks interact with environmental adversities early in life, modifying endophenotypes (impulsivity, sensitivity to reward, executive function, food choices) that ultimately affect healthy growth and neurodevelopment, increasing an individual’s risk for developing chronic metabolic diseases and psychopathologies across their lifespan.
Presentations

A mesocorticolimbic dopamine gene network moderates the effect of early adversity on the risk for metabolic and psychiatric comorbidities
Barbara Barth and 4 other authors

The role of dopamine on the link between early life environment and lifecourse eating behavior and co-morbidity between metabolic and psychiatric disorders: Context characterization and biologically-informed genomic approaches
Patricia Pelufo Silveira and 4 other authors