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This paper outlines our submission to the MEDIQA2024 Multilingual and Multimodal Medical Answer Generation (M3G) shared task. We report results for two standalone solutions under the English category of the task, the first involving two consecutive API calls to the Claude 3 Opus API and the second involving training an image-disease label joint embedding in the style of CLIP for image classification. These two solutions scored 1st and 2nd place respectively on the competition leaderboard, substantially outperforming the next best solution. Additionally, we discuss insights gained from post-competition experiments. While the performance of these two described solutions have significant room for improvement due to the difficulty of the shared task and the challenging nature of medical visual question answering in general, we identify the multi-stage LLM approach and the CLIP image classification approach as promising avenues for further investigation.

WangLab at MEDIQA-M3G 2024: Multimodal Medical Answer Generation using Large Language Models

Recently, deep learning-based language models have significantly enhanced text-to-SQL tasks, with promising applications in retrieving patient records within the medical domain. One notable challenge in such applications is discerning unanswerable queries. Through fine-tuning model, we demonstrate the feasibility of converting medical record inquiries into SQL queries. Additionally, we introduce an entropy-based method to identify and filter out unanswerable results. We further enhance result quality by filtering low-confidence SQL through log probability-based distribution, while grammatical and schema errors are mitigated by executing queries on the actual database.
We experimentally verified that our method can filter unanswerable questions, which can be widely utilized even when the parameters of the model are not accessible, and that it can be effectively utilized in practice.

ProbGate at EHRSQL 2024: Enhancing SQL Query Generation Accuracy through Probabilistic Threshold Filtering and Error Handling

The EHRSQL task aims to develop a dependable text-to-SQL model for Electronic Health Records (EHR) databases, which are crucial sources of clinical data that store patients' medical histories in hospitals. Large language models (LLM) have been proven to exhibit state-of-the-art performance for text-to-SQL tasks across various domains. To this end, we have developed a framework, SQL Generation through Classification Answer Selector by LLM (SCAS), which comprises two modules. The CAS module determines the answerability of the question, while the SG model generates the SQL query exclusively for answerable questions. Our system ranked 7th on the leaderboard with a Reliability Score of 53.21 on the official test set.

Saama Technologies at EHRSQL 2024: SQL Generation through Classification Answer Selector by LLM

Electronic Health Records (EHRs) are relational databases that store the entire medical histories of patients within hospitals. They record numerous aspects of patients' medical care, from hospital admission and diagnosis to treatment and discharge. While EHRs are vital sources of clinical data, exploring them beyond a predefined set of queries requires skills in query languages like SQL. To make information retrieval more accessible, one strategy is to build a question-answering system, possibly leveraging text-to-SQL models that can automatically translate natural language questions into corresponding SQL queries and use these queries to retrieve the answers. The EHRSQL 2024 shared task aims to advance and promote research in developing a question-answering system for EHRs using text-to-SQL modeling, capable of reliably providing requested answers to various healthcare professionals to improve their clinical work processes and satisfy their needs. Among more than 100 participants who applied to the shared task, eight teams completed the entire shared task processes and demonstrated a wide range of methods to effectively solve this task. In this paper, we describe the task of reliable text-to-SQL modeling, the dataset, and the methods and results of the participants. We hope this shared task will spur further research and insights into developing reliable question-answering systems for EHRs.

Overview of the EHRSQL 2024 Shared Task on Reliable Text-to-SQL Modeling on Electronic Health Records

This paper presents our approach for the 2024 ChemoTimelines shared task. Specifically, we explored using Large Language Models (LLMs) for temporal relation extraction. We evaluate multiple model variations based on how the training data is used. For instance, we transform the task into a question-answering problem and use QA pairs to extract chemo-related events and their temporal relations. Next, we add all the documents to each question-answer pair as examples in our training dataset. Finally, we explore adding unlabeled data for continued pretraining. Each addition is done iteratively. Our results show that adding the document helps, but unlabeled data does not yield performance improvements, possibly because we used only 1\% of the available data. Moreover, we find that instruction-tuned models still substantially underperform more traditional systems (e.g., EntityBERT).

UTSA-NLP at ChemoTimelines 2024: Evaluating Instruction-Tuned Language Models for Temporal Relation Extraction

In natural language processing applied to the clinical domain, utilizing large language models has emerged as a promising avenue for error detection and correction on clinical notes, a knowledge-intensive task for which annotated data is scarce. This paper presents MedReAct'N'MedReFlex, which leverages a suite of four LLM-based medical agents. The MedReAct agent initiates the process by observing, analyzing, and taking action, generating trajectories to guide the search to target a potential error in the clinical notes. Subsequently, the MedEval agent employs five evaluators to assess the targeted error and the proposed correction. In cases where MedReAct's actions prove insufficient, the MedReFlex agent intervenes, engaging in reflective analysis and proposing alternative strategies. Finally, the MedFinalParser agent formats the final output, preserving the original style while ensuring the integrity of the error correction process. One core component of our method is our RAG pipeline based on our ClinicalCorp corpora. Among other well-known sources containing clinical guidelines and information, we preprocess and release the open-source MedWiki dataset for clinical RAG application. Our results demonstrate the central role of our RAG approach with ClinicalCorp leveraged through the MedReAct'N'MedReFlex framework. It achieved the ninth rank on the MEDIQA-CORR 2024 final leaderboard.

IryoNLP at MEDIQA-CORR 2024: Tackling the Medical Error Detection & Correction Task on the Shoulders of Medical Agents

The 2024 Shared Task on Chemotherapy Treatment Timeline Extraction aims to advance the state of the art of clinical event timeline extraction from the Electronic Health Records (EHRs). Specifically, this edition focuses on chemotherapy event timelines from EHRs of patients with breast, ovarian and skin cancers. These patient-level timelines present a novel challenge which involves tasks such as the extraction of relevant events, time expressions and temporal relations from each document and then summarizing over the documents. De-identified EHRs for 57,530 patients with breast and ovarian cancer spanning 2004-2020, and approximately 15,946 patients with melanoma spanning 2010-2020 were made available to participants after executing a Data Use Agreement. A subset of patients is annotated for gold entities, time expressions, temporal relations and patient-level timelines. The rest is considered unlabeled data. In Subtask1, gold chemotherapy event mentions and time expressions are provided (along with the EHR notes). Participants are asked to build the patient-level timelines using gold annotations as input. Thus, the subtask seeks to explore the topics of temporal relations extraction and timeline creation if event and time expression input is perfect. In Subtask2, which is the realistic real-world setting, only EHR notes are provided. Thus, the subtask aims at developing an end-to-end system for chemotherapy treatment timeline extraction from patient's EHR notes. There were 18 submissions for Subtask 1 and 9 submissions for Subtask 2. The organizers provided a baseline system. The teams employed a variety of methods including Logistic Regression, TF-IDF, n-grams, transformer models, zero-shot prompting with Large Language Models (LLMs), and instruction tuning. The gap in performance between prompting LLMs and finetuning smaller-sized LMs indicates that for a challenging task such as patient-level chemotherapy timeline extraction, more sophisticated LLMs or prompting techniques are necessary in order to achieve optimal results as finetuing smaller-sized LMs outperforms by a wide margin.

Overview of the 2024 Shared Task on Chemotherapy Treatment Timeline Extraction

The automatic identification of medical errors in clinical notes is crucial for improving the quality of healthcare services.LLMs emerge as a powerful artificial intelligence tool for automating this task. However, LLMs present vulnerabilities, high costs, and sometimes a lack of transparency. This article addresses the detection of medical errors through the fine-tuning approach, conducting a comprehensive comparison between various models and exploring in depth the components of the machine learning pipeline. The results obtained with the fine-tuned ClinicalBert and Gated recurrent units (Gru) models show an accuracy of 0.56 and 0.55, respectively. This approach not only mitigates the problems associated with the use of LLMs but also demonstrates how exhaustive iteration in critical phases of the pipeline, especially in feature selection, can facilitate the automation of clinical record analysis.

VerbaNexAI at MEDIQA-CORR: Efficacy of GRU with BioWordVec and ClinicalBERT in Error Correction in Clinical Notes

In this paper, we report our effort to tackle the challenge of extracting chemotimelines from EHR notes across a dataset of three cancer types. We focus on the two subtasks: 1) detection and classification of temporal relations given the annotated chemotherapy events and time expressions and 2) directly extracting patient chemotherapy timelines from EHR notes. We address both subtasks using Large Language Models. Our best-performing methods in both subtasks use Flan-T5, an instruction-tuned language model. Our proposed system achieves the highest average score in both subtasks. Our results underscore the effectiveness of finetuning general-domain large language models in domain-specific and unseen tasks.

LAILab at Chemotimelines 2024: Finetuning sequence-to-sequence language models for temporal relation extraction towards cancer patient undergoing chemotherapy treatment

This paper describes our approach to the MEDIQA-CORR shared task, which involves error detection and correction in clinical notes curated by medical professionals. This task involves handling three subtasks: detecting the presence of errors, identifying the specific sentence containing the error, and correcting it. Through our work, we aim to assess the capabilities of Large Language Models (LLMs) trained on a vast corpora of internet data that contain both factual and unreliable information. We propose to comprehensively address all subtasks together, and suggest employing a unique prompt-based in-context learning strategy. We will evaluate its efficacy in this specialized task demanding a combination of general reasoning and medical knowledge. In medical systems where prediction errors can have grave consequences, we propose leveraging self-consistency and ensemble methods to enhance error correction and error detection performance.

PromptMind Team at MEDIQA-CORR 2024: Improving Clinical Text Correction with Error Categorization and LLM Ensembles

This paper describes our submission to the MEDIQA-CORR 2024 shared task for automatically detecting and correcting medical errors in clinical notes. We report results for three methods of few-shot In-Context Learning (ICL) augmented with Chain-of-Thought (CoT) and reason prompts using a large language model (LLM). In the first method, we manually analyse a subset of train and validation dataset to infer three CoT prompts by examining error types in the clinical notes. In the second method, we utilise the training dataset to prompt the LLM to deduce reasons about their correctness or incorrectness. The constructed CoTs and reasons are then augmented with ICL examples to solve the tasks of error detection, span identification, and error correction. Finally, we combine the two methods using a rule-based ensemble method. Across the three sub-tasks, our ensemble method achieves a ranking of 3rd for both sub-task 1 and 2, while securing 7th place in sub-task 3 among all submissions.

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Live - Hunter Gatherer Education Working Group

WangLab at MEDIQA-M3G 2024: Multimodal Medical Answer Generation using Large Language Models

ProbGate at EHRSQL 2024: Enhancing SQL Query Generation Accuracy through Probabilistic Threshold Filtering and Error Handling

Saama Technologies at EHRSQL 2024: SQL Generation through Classification Answer Selector by LLM

Overview of the EHRSQL 2024 Shared Task on Reliable Text-to-SQL Modeling on Electronic Health Records

UTSA-NLP at ChemoTimelines 2024: Evaluating Instruction-Tuned Language Models for Temporal Relation Extraction

IryoNLP at MEDIQA-CORR 2024: Tackling the Medical Error Detection & Correction Task on the Shoulders of Medical Agents

Overview of the 2024 Shared Task on Chemotherapy Treatment Timeline Extraction

VerbaNexAI at MEDIQA-CORR: Efficacy of GRU with BioWordVec and ClinicalBERT in Error Correction in Clinical Notes

LAILab at Chemotimelines 2024: Finetuning sequence-to-sequence language models for temporal relation extraction towards cancer patient undergoing chemotherapy treatment

PromptMind Team at MEDIQA-CORR 2024: Improving Clinical Text Correction with Error Categorization and LLM Ensembles

KnowLab_AIMed at MEDIQA-CORR 2024: Chain-of-Though (CoT) prompting strategies for medical error detection and correction

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