In recent years, the COVID-19 virus pandemic has threatened public health globally. In several nations, the pandemic's aftermath is still affecting the human population. Numerous mutant strains of SARS CoV-2 spreading caused several waves of infection. These variants were linked to high infectivity or high mortality. But in the face of such assaults, human immune system developed a defence mechanism of its own against the infection to deal with cytokine storm, antibody neutralization escape and multiple organ failure. In order to boost the defence mechanism and SARS CoV-2 broadly being a respiratory disorder was targeted with multiple remedial strategies procured from traditional knowledge of medicinal plants. A survey was conducted to surmise the usage of such medicinal plants with therapeutic properties during the pandemic in a random population in West Bengal, India. Our data demonstrates the most often utilized raw traditional medicines. To deal with clinical manifestations associated with SARS CoV-2 (such as cough and cold) and boosting immunity, Tulsi (Ocimum tenuiflorum) was the most widely used plant which is easy to manage in kitchen gardens and have a high growth rate on the Indian subcontinent. This survey-based study is done to correlate with the efficacy of Tulsi in combating infectious diseases from common cough and cold to COVID-19. Regulated long-term use of these medicinal plants will also help avoid a number of prevalent illnesses and be advantageous for household healthcare.