Canada

Machine reasoning has made great progress in recent years owing to large language models (LLMs). In the clinical domain, however, most NLP-driven projects mainly focus on clinical classification or reading comprehension, and under-explore clinical reasoning for disease diagnosis due to the expensive rationale annotation with clinicians. In this work, we present a &quot;reasoning-aware&quot; diagnosis framework that rationalizes the diagnostic process via prompt-based learning in a time- and labor-efficient manner, and learns to reason over the prompt-generated rationales. Specifically, we address the clinical reasoning for disease diagnosis, where the LLM generates diagnostic rationales providing its insight on presented patient data and the reasoning path towards the diagnosis, namely Clinical Chain-of-Thought (Clinical CoT). We empirically demonstrate LLMs/LMs&#39; ability of clinical reasoning via extensive experiments and analyses on both rationale generation and disease diagnosis in various settings. We further propose a novel set of criteria for evaluating machine-generated rationales&#39; potential for real-world clinical settings, facilitating and benefiting future research in this area.

AAAI 2024

Large Language Models Are Clinical Reasoners: Reasoning-Aware Diagnosis Framework with Prompt-Generated Rationales

chain-of-thought

large language model

distillation

medical

reasoning

clinical

Machine reasoning has made great progress in recent years owing to large language models (LLMs). In the clinical domain, however, most NLP-driven projects mainly focus on clinical classification or reading comprehension, and under-explore clinical reasoning for disease diagnosis due to the expensive rationale annotation with clinicians. In this work, we present a "reasoning-aware" diagnosis framework that rationalizes the diagnostic process via prompt-based learning in a time- and labor-efficient manner, and learns to reason over the prompt-generated rationales. Specifically, we address the clinical reasoning for disease diagnosis, where the LLM generates diagnostic rationales providing its insight on presented patient data and the reasoning path towards the diagnosis, namely Clinical Chain-of-Thought (Clinical CoT). We empirically demonstrate LLMs/LMs' ability of clinical reasoning via extensive experiments and analyses on both rationale generation and disease diagnosis in various settings. We further propose a novel set of criteria for evaluating machine-generated rationales' potential for real-world clinical settings, facilitating and benefiting future research in this area.

technical paper

We are pleased to announce the Thirty-Eighth AAAI Conference on Artificial Intelligence (AAAI-24), which will be held in Vancouver, British Columbia at the Vancouver Convention Centre – West Building from 20-27 February, 2024.

The purpose of the AAAI conference series is to promote research in Artificial Intelligence (AI) and foster scientific exchange between researchers, practitioners, scientists, students, and engineers across the entirety of AI and its affiliated disciplines. AAAI-24 will feature technical paper presentations, special tracks, invited speakers, workshops, tutorials, poster sessions, senior member presentations, competitions, and exhibit programs, and a range of other activities to be announced.

We expect for AAAI-24 to be an in-person conference – one author of all accepted papers will be expected to present work in person unless there are exceptional circumstances that prevent this.<br><br><br><br>

In order to access the AAAI-24 event page you need to register [here](https://aaai.org/aaai-conference/registration/)

The purpose of the AAAI conference series is to promote research in Artificial Intelligence (AI) and foster scientific exchange between researchers, practitioners, scientists, students, and engineers across the entirety of AI and its affiliated disciplines. 

Graph neural networks (GNNs) and heterogeneous graph neural networks (HGNNs) are prominent techniques for homogeneous and heterogeneous graph representation learning, yet their performance in an end-to-end supervised framework greatly depends on the availability of task-specific supervision. To reduce the labeling cost, pre-training on self-supervised pretext tasks has become a popular paradigm, but there is often a gap between the pre-trained model and downstream tasks, stemming from the divergence in their objectives. To bridge the gap, prompt learning has risen as a promising direction especially in few-shot settings, without the need to fully fine-tune the pre-trained model. While there has been some early exploration of prompt-based learning on graphs, they primarily deal with homogeneous graphs, ignoring the heterogeneous graphs that are prevalent in downstream applications. In this paper, we propose HGPROMPT, a
novel pre-training and prompting framework to unify not only pre-training and downstream tasks but also homogeneous and heterogeneous graphs via a dual-template design. Moreover, we propose dual-prompt in HGPROMPT to assist a downstream task in locating the most relevant prior to bridge the gaps caused by not only feature variations but also heterogeneity differences across tasks. Finally, we thoroughly evaluate and analyze HGPROMPT through extensive experiments
on three public datasets.

HGPrompt: Bridging Homogeneous and Heterogeneous Graphs for Few-Shot Prompt Learning

Asking questions about visual environments is a crucial way for intelligent agents to understand rich multi-faceted scenes, raising the importance of Visual Question Generation (VQG) systems. Apart from being grounded to the image, existing VQG systems can use textual constraints, such as expected answers or knowledge triplets, to generate focused questions. These constraints allow VQG systems to specify the question content or leverage external commonsense knowledge that can not be obtained from the image content only. However, generating focused questions using textual constraints while enforcing a high relevance to the image content remains a challenge, as VQG systems often ignore one or both forms of grounding. In this work, we propose Contrastive Visual Question Generation (ConVQG), a method using a dual contrastive objective to discriminate questions generated using both modalities from those based on a single one. Experiments on both knowledge-aware and standard VQG benchmarks demonstrate that ConVQG outperforms the state-of-the-art methods and generates image-grounded, text-guided, and knowledge-rich questions. Our human evaluation results also show preference for ConVQG questions compared to non-contrastive baselines.

ConVQG: Contrastive Visual Question Generation with Multimodal Guidance

Multi-modal aspect-based sentiment analysis (MABSA) has recently attracted increasing attention. 
The span-based extraction methods, such as FSUIE, demonstrate strong performance in sentiment analysis due to their joint modeling of input sequences and target labels. However, previous methods still have certain limitations:
(i) They ignore the difference in the focus of visual information between different analysis targets (aspect or sentiment).
(ii) Combining features from uni-modal encoders directly may not be sufficient to eliminate the modal gap and can cause difficulties in capturing the image-text pairwise relevance.
(iii) Existing span-based methods for MABSA ignore the pairwise relevance of target span boundaries.
To tackle these limitations, we propose a novel framework called DQPSA. Specifically, our model contains a Prompt as Dual Query (PDQ) module that uses the prompt as both a visual query and a language query to extract prompt-aware visual information and strengthen the pairwise relevance between visual information and the analysis target. Additionally, we introduce an Energy-based Pairwise Expert (EPE) module that models the boundaries pairing of the analysis target from the perspective of an Energy-based Model. This expert predicts aspect or sentiment span based on pairwise stability.
Experiments on three widely used benchmarks demonstrate that DQPSA outperforms previous approaches and achieves a new state-of-the-art performance.

A Novel Energy Based Model Mechanism for Multi-Modal Aspect-Based Sentiment Analysis

The recent proliferation of research into transformer based natural language processing has led to a number of studies which attempt to detect the presence of human-like cognitive behavior in the models. We contend that, as is true of human psychology, the investigation of cognitive behavior in language models must be conducted in an appropriate population of an appropriate size for the results to be meaningful. We leverage work in uncertainty estimation in a novel approach to efficiently construct experimental populations. The resultant tool, PopulationLM, has been made open source. We provide theoretical grounding in the uncertainty estimation literature and motivation from current cognitive work regarding language models. We discuss the methodological lessons from other scientific communities and attempt to demonstrate their application to two artificial population studies. Through population based experimentation we find that language models exhibit behavior consistent with typicality effects among categories highly represented in training. However, we find that language models don't tend to exhibit structural priming effects. Generally, our results show that single models tend to over estimate the presence of cognitive behaviors in neural models.

Using Artificial Populations to Study Psychological Phenomena in Neural Models

Multi-task learning (MTL) is essential for real-world applications that handle multiple tasks simultaneously, such as selfdriving cars. MTL methods improve the performance of all tasks by utilizing information across tasks to learn a robust shared representation. However, acquiring sufficient labeled data tends to be extremely expensive, especially when having to support many tasks. Recently, Knowledge Amalgamation (KA) has emerged as an effective strategy for addressing the lack of labels by instead learning directly from pretrained models (teachers). KA learns one unified multi-task student that masters all tasks across all teachers. Existing KA for MTL works are limited to teachers with identical architectures, and thus propose layer-to-layer based approaches. Unfortunately, in practice, teachers may have heterogeneous architectures; their layers may not be aligned and their dimensionalities or scales may be incompatible. Amalgamating multi-task teachers with heterogeneous architectures remains an open problem. For this, we design Versatile Common Feature Consolidator (VENUS), the first solution to this problem. VENUS fuses knowledge from the shared representations of each teacher into one unified generalized representation for all tasks. Specifically, we design the Feature Consolidator network that leverages an array of teacher-specific trainable adaptors. These adaptors enable the student to learn from multiple teachers, even if they have incompatible learned representations. We demonstrate that VENUS outperforms five alternative methods on numerous benchmark datasets across a broad spectrum of experiments.

Amalgamating Multi-Task Models with Heterogeneous Architectures

Biologically Inspired Design (BID), or Biomimicry, is a problem-solving methodology that applies analogies from nature to solve engineering challenges. For example, Speedo engineers designed swimsuits based on shark skin. Finding relevant biological solutions for real-world problems poses significant challenges, both due to the limited biological knowledge engineers and designers typically possess and to the limited BID resources. Existing BID datasets are hand-curated and small, and scaling them up requires costly human annotations.

In this paper, we introduce BARcode (Biological Analogy Retriever), a search engine for automatically mining bio-inspirations from the web at scale. Using advances in natural language understanding and data programming, BARcode identifies potential inspirations for engineering challenges. Our experiments demonstrate that BARcode can retrieve inspirations that are valuable to engineers and designers tackling real-world problems, as well as recover famous historical BID examples. We release data and code; we view BARcode as a step towards addressing the challenges that have historically hindered the practical application of BID to engineering innovation.

Imitation of Life: A Search Engine for Biologically Inspired Design | VIDEO

Learning in games considers how multiple agents maximize their own rewards through repeated games. Memory, an ability that an agent changes his/her action depending on the history of actions in previous games, is often introduced into learning to explore more clever strategies and discuss the decision-making of real agents like humans. However, such games with memory are hard to analyze because they exhibit complex phenomena like chaotic dynamics or divergence from Nash equilibrium. In particular, how asymmetry in memory capacities between agents affects learning in games is still unclear. In response, this study formulates a gradient ascent algorithm in games with asymmetry memory capacities. To obtain theoretical insights into learning dynamics, we first consider a simple case of zero-sum games. We observe complex behavior, where learning dynamics draw a heteroclinic connection from unstable fixed points to stable ones. Despite this complexity, we analyze learning dynamics and prove local convergence to these stable fixed points, i.e., the Nash equilibria. We identify the mechanism driving this convergence: an agent with a longer memory learns to exploit the other, which in turn endows the other's utility function with strict concavity. We further numerically observe such convergence in various initial strategies, action numbers, and memory lengths. This study reveals a novel phenomenon due to memory asymmetry, providing fundamental strides in learning in games and new insights into computing equilibria.

Memory Asymmetry Creates Heteroclinic Orbits to Nash Equilibrium in Learning in Zero-Sum Games

Slow concept drift is a ubiquitous, yet under-studied problem in practical machine learning systems. Although recent data is more indicative of future data in these settings, naively prioritizing these instances runs the risk of losing valuable information from the past. We propose an optimization-driven approach towards balancing instance importance over large training windows. First, we model instance relevance using a mixture of multiple timescales of decay, allowing us to capture rich temporal trends. Second, we learn an auxiliary scorer model that recovers the appropriate mixture of timescales as a function of the instance itself. Finally, we propose a nested optimization objective for learning the scorer, by which it maximizes forward transfer for the learned model. Experiments on a large real-world dataset of 39M photos over a 9 year period show upto 15% relative gains in accuracy compared to other robust learning baselines. We replicate our gains on two collections of real-world datasets for non-stationary learning, and extend our work to continual learning settings where, too, we beat SOTA methods by large margins.

Instance-Conditional Timescales of Decay for Nonstationary Learning

Convolutional Neural Networks (CNNs) have exhibited great performance in discriminative feature learning for complex visual tasks. Besides discrimination power, interpretability is another important yet under-explored property for CNNs. One difficulty in the CNN interpretability is that filters and image classes are entangled. In this paper, we introduce a novel pathway to alleviate the entanglement between filters and image classes. The proposed pathway groups the filters in a late conv-layer of CNN into class-specific clusters. Clusters and classes are in a one-to-one relationship. Specifically, we use the Bernoulli sampling to generate the filter-cluster assignment matrix from a learnable filter-class correspondence matrix. To enable end-to-end optimization, we develop a novel reparameterization trick for handling the non-differentiable Bernoulli sampling. We evaluate the effectiveness of our method on ten widely used network architectures (including nine CNNs and a ViT) and five benchmark datasets. Experimental results have demonstrated that our method PICNN (the combination of standard CNNs with our proposed pathway) exhibits greater interpretability than standard CNNs while achieving higher or comparable discrimination power.

PICNN: A Pathway towards Interpretable Convolutional Neural Networks

Few-shot segmentation aims to accurately segment novel target objects within query images using only a limited number of annotated support images. The recent works exploit support background as well as its foreground to precisely compute the dense correlations between query and support. However, they overlook the characteristics of the background that generally contains various types of objects. In this paper, we highlight this characteristic of background which can bring problematic cases as follows: (1) when the query and support backgrounds are dissimilar and (2) when objects in the support background are similar to the target object in the query. Without any consideration of the above cases, adopting the entire support background leads to a misprediction of the query foreground as background. To address this issue, we propose Task-disruptive Background Suppression(TBS), a module to suppress those disruptive support background features based on two spatial-wise scores: query-relevant and target-relevant scores. The former aims to mitigate the impact of unshared features solely existing in the support background, while the latter aims to reduce the influence of target-similar support background features. Based on these two scores, we define a query background relevant score that captures the similarity between the backgrounds of the query and the support, and utilize it to scale support background features to adaptively restrict the impact of disruptive support backgrounds. Our proposed method achieves state-of-the-art performance on PASCAL and COCO datasets on 1-shot segmentation. Our codes are available at github.com/SuhoPark0706/TBSNet

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Large Language Models Are Clinical Reasoners: Reasoning-Aware Diagnosis Framework with Prompt-Generated Rationales

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