Canada

We describe the participation of team e-Health CSIRO in the BioNLP RadSum task of 2023. This task aims to develop automatic summarisa- tion methods for radiology. The subtask that we participated in was multimodal; the impression section of a report was to be summarised from a given findings section and set of Chest X-rays (CXRs) of a subject’s study. For our method, we adapted an encoder-to-decoder model for CXR report generation to the subtask. e-Health CSIRO placed seventh amongst the participat- ing teams with a RadGraph ER F1 score of 23.9.

ACL 2023

Sentiment-guided Transformer with Severity-aware Contrastive Learning for Depression Detection on Social Media

multimodal radiology report summarisation

workshop paper

### Welcome to ACL 2023, the 61st Annual Meeting of the Association for Computational Linguistics! 
 The conference will be held in Toronto, Canada, July 9-14, 2023. 
Following the succession of the recent conferences in our field, ACL 2023 will adopt a hybrid format.
While the impact of Covid has considerably diminished in terms of traveling, obtaining visas to Canada
entails a very long process. Moreover, the global economic conditions pose challenges for many individuals to travel to conferences. Recognizing these circumstances, we know many participants may not be
able to attend the conference in person. Therefore, we are committed to providing a great virtual platform
so everyone has the opportunity to interact with other participants and enjoy the conference. Based on the
current registered participants, approxiately 30% have chosen to attend the conference virtually. Whether
you join us in person or virtually, we sincerely hope everyone has a remarkable conference experience. 
This General Chair’s message is where I express my gratitude to the many individuals who have made
enormous contributions to the conference over the past year.

Read [**ACL 2023 General Chair's message**](https://docs.google.com/document/d/1WobYM7norbG4dI48s75HfJoD89qgX5a_F-6U8AteLSA/edit?usp=sharing/) in full.

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The Association for Computational Linguistics (ACL) is the premier international scientific and professional society for people working on computational problems involving human language, a field often referred to as either computational linguistics or natural language processing.

Social media (SM) can provide valuable information about patients' experiences with multiple drugs during treatments. Although information extraction from SM has been well-studied, drug switches detection and reasons behind these switches from SM have not been studied yet. Therefore, in this paper, we present a new SM listening approach for analyzing online patient conversations that contain information about drug switching, drug effectiveness, side effects, and adverse drug reactions. We describe a deep learning-based approach for identifying instances of drug switching in SM posts, as well as a method for extracting the reasons behind these switches. To train and test our models, we used annotated SM data from internal dataset which is automatically created using a rule-based method. We evaluated our models using Text-to-Text Transfer Transformer (T5) and found that our SM listening approach can extract medication change information and reasons with high accuracy, achieving an F1-score of 98% and a ROUGE-1 score of 93%, respectively. Overall, our results suggest that our SM listening approach has the potential to provide valuable insights into patients' experiences with drug treatments, which can be used to improve patient outcomes and the effectiveness of drug treatments.

Exploring Drug Switching in Patients: A Deep Learning-based Approach to Extract Drug Changes and Reasons from Social Media


The use of seed articles in information retrieval provides many advantages, such as a longer context and more details about the topic being searched for. Given a seed article (i.e., a PMID), PubMed provides a pre-compiled list of similar articles to support the user in finding equivalent papers in the biomedical literature. We aimed at performing a quantitative evaluation of the PubMed Similar Articles based on three existing biomedical text similarity datasets, namely, RELISH, TREC-COVID, and SMAFIRA-c. Further, we carried out a survey and an evaluation of various text similarity methods on these three datasets. Our experiments considered the original title and abstract from PubMed as well as automatically detected sections and manually annotated relevant sentences. We provide an overview about which methods better perform for each dataset and compare them to the ranking in PubMed similar articles. While results varied considerably among the datasets, we were able to obtain a better performance than PubMed for all of them. Datasets and source codes are available at: https://github.com/mariananeves/reranking

Is the ranking of PubMed similar articles good enough? An evaluation of text similarity methods for three datasets

We propose a novel distantly supervised document-level biomedical relation extraction model that uses partial knowledge graphs that include the graph neighborhood of the entities appearing in each input document. 
Most conventional distantly supervised relation extraction methods use only the entity relations automatically annotated by using knowledge base entries. They do not fully utilize the rich information in the knowledge base, such as entities other than the target entities and the network of heterogeneous entities defined in the knowledge base.
To address this issue, our model integrates the representations of the entities acquired from the neighborhood knowledge graphs with the representations of the input document. 
We conducted experiments on the ChemDisGene dataset using Comparative Toxicogenomics Database (CTD) for document-level relation extraction with respect to interactions between drugs, diseases, and genes. 
Experimental results confirmed the performance improvement by integrating entities and their neighborhood biochemical information from the knowledge base.

Distantly Supervised Document-Level Biomedical Relation Extraction with Neighborhood Knowledge Graphs

We propose a distantly supervised pipeline NER which executes entity span detection and entity classification in sequence named DISTANT (DIstantly Supervised entiTity spAN deTection and classification).
The former entity span detector extracts possible entity mention spans by the distant supervision. Then the later entity classifier assigns each entity span to one of the positive entity types or none by employing a positive and unlabeled (PU) learning framework. Two models were built based on the pre-trained SciBERT model and fine-tuned with the silver corpus generated by the distant supervision.
Experimental results on BC5CDR and NCBI-Disease datasets show that our method outperforms the end-to-end NER baselines without PU learning by a large margin. In particular, it increases the recall score effectively.

DISTANT: Distantly Supervised Entity Span Detection and Classification

Early identification of Adverse Drug Events (ADE) is critical for taking prompt actions while introducing new drugs into the market. These ADEs information are available through various unstructured data sources like clinical study reports, patient health records, social media posts, etc. Extracting ADEs and the related suspect drugs using machine learning is a challenging task due to the complex linguistic relations between drug – ADE pairs in textual data and unavailability of large corpus of labelled datasets. This paper introduces ADEQA, a question- answer(QA) based approach using quasi supervised labelled data and sequence-to-sequence transformers to extract ADEs, drug suspects and the relationships between them. Unlike traditional QA models, natural language generation (NLG) based models don't require extensive token level labelling and thereby reduces the adoption barrier significantly. On a public ADE corpus, we were able to achieve state-of-the-art results with an F1 score of 94% on establishing the relationships between ADEs and the respective suspects.

ADEQA: A Question Answer based approach for joint ADE-Suspect Extraction using Sequence-To-Sequence Transformers

Accurate human-annotated data for real-world use cases can be scarce and expensive to obtain. In the clinical domain, obtaining such data is even
more difficult due to privacy concerns which not only restrict open access to quality data but also require that the annotation be done by domain experts. In this paper, we propose a novel framework - InterDAPT - that leverages Intermediate Domain Finetuning to allow language models to adapt to narrow domains with small, noisy datasets. By making use of peripherally-related, unlabeled datasets, this framework circumvents domain-specific data scarcity issues. Our results show that this weakly
supervised framework provides performance improvements in downstream clinical named entity recognition tasks.

Intermediate Domain Finetuning for Weakly Supervised Domain-adaptive Clinical NER

Biomedical event extraction can be divided into three main subtasks; (1) biomedical event trigger detection, (2) biomedical argument identification and (3) event construction. This work focuses in the two first subtasks. For the first subtask we analyze a set of transformer language models that are commonly used in the biomedical domain to evaluate and compare their capacity for event trigger detection. We fine-tune the models using seven manually annotated corpora to assess their performance in different biomedical subdomains. SciBERT emerged as the highest performing model, presenting a slight improvement compared to baseline models. Then, for the second subtask we construct a knowledge graph (KG) from the biomedical corpora and integrate its KG embeddings to SciBERT to enrich its semantic information. We demonstrate that adding the KG embeddings to the model improves the argument identification performance by around 20 \%, and by around 15 \% compared to two baseline models. Our results suggest that fine-tuning a transformer model that is pretrained from scratch with biomedical and general data allows to detect event triggers and identify arguments covering different biomedical subdomains, and therefore improving its generalization. Furthermore, the integration of KG embeddings into the model can significantly improve the performance of biomedical event argument identification, outperforming the results of baseline models.

How Much do Knowledge Graphs Impact Transformer Models for Extracting Biomedical Events?

Recently, several methods have tackled the relation extraction task with QA and have shown successful results. However, the effectiveness of existing methods in specific domains, such as the biomedical domain, is yet to be verified. When there are multiple entity pairs that share an entity in a sentence, a QA-based relation extraction model that outputs only one single answer to a given question may not extract desired relations. In addition, these methods employ QA models that are not tuned for relation extraction. To address these issues, we first extend and apply a span QA-based relation extraction method to the drug-protein relation extraction by creating question templates and incorporating entity type markers. We further propose a binary QA-based method that directly uses the entity information available in the relation extraction task. The experimental results on the DrugProt dataset show that our QA-based methods, especially the proposed binary QA method, are effective for drug-protein relation extraction.

Biomedical Relation Extraction with Entity Type Markers and Relation-specific Question Agnswerin

Social media platforms have enabled individuals suffering from mental illnesses to share their lived experiences and find the online support necessary to cope. However, many users fail to receive genuine clinical support, thus exacerbating their symptoms. Screening users based on what they post online can aid providers in administering targeted healthcare and minimize false positives. Pre-trained Language Models (LMs) can assess users' social media data and classify them in terms of their mental health risk. We propose a Question-Answering (QA) approach to assess mental health risk using the Unified-QA model on two large mental health datasets. To protect user data, we extend Unified-QA by anonymizing the model training process using differential privacy. Our results demonstrate the effectiveness of modeling risk assessment as a QA task, specifically for mental health use cases. Furthermore, the model's performance decreases by less than 1% with the inclusion of differential privacy. The proposed system's performance is indicative of a promising research direction that will lead to the development of privacy-aware diagnostic systems.

Privacy Aware Question-Answering System for Online Mental Health Risk Assessment

This paper describes the submission of the TALP-UPC team to the Problem List Summarization task from the BioNLP 2023 workshop. This task consists of automatically extracting a list of health issues from the e-health medical record of a given patient. Our submission combines additional steps of data annotation with finetuning of BERT pre-trained language models. Our experiments focus on the impact of finetuning on different datasets as well as the addition of data augmentation techniques to delay overfitting.

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Sentiment-guided Transformer with Severity-aware Contrastive Learning for Depression Detection on Social Media

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