Lecture image placeholder

Premium content

Access to this content requires a subscription. You must be a premium user to view this content.

Monthly subscription - $9.99Pay per view - $4.99Access through your institutionLogin with Underline account
Need help?
Contact us
Lecture placeholder background
VIDEO DOI: https://doi.org/10.48448/131p-9z45

technical paper

MMM 2022

November 07, 2022

Minneapolis, United States

Wireless temperature monitoring by using magnetic nanoparticles for clinical trials on magnetic hyperthermia treatment

Magnetic hyperthermia with magnetic nanoparticles (MNPs) has been introduced to selective treatment of tumor 1,2 and the MNPs also has demonstrated diagnosis 3, 4. For non-invasive treatment, a therapeutic system with a temperature monitoring that can avoid overheating in normal tissues is of vital importance. We have developed a temperature monitoring/control system with an optical fiber temperature probe in vivo 2. However, the optical fiber involves an invasive measurement due to the contact with the body. In this study, we have developed a wireless temperature monitoring system by utilizing the combination of magnetic harmonic signals of the MNPs for clinical trials. Figure 1 shows the developed wireless monitoring system with Resovist® (a clinically approved MNP). Under the application of alternating magnetic fields, the detected harmonics were analyzed to extract only temperature-dependent signals. Figure 2 shows the measured temperature of Resovist® phantom. We achieved an accurate measurement with an error of 0.18°C (Fig. 2(a)). For practical use on breast/oral cancer, a detectable distance of 10 mm is required. We measured the accurate temperature at a 10 mm distance (Fig. 2(b)). To demonstrate the feasibility toward clinical trials, we investigated the dependency on the detectable distance and the amount of Resovist®. The error is less than 0.5°C in a 10 mm distance (Fig. 2(c)). Resovist® travels to the whole body from the injection site via the lymphatic system, resulting in a decrement of the amount at the injection site. Our system can measure the correct temperature regardless of Resovist® amount (Fig. 2(d)). The results indicate that our system can apply to clinical trials. We will pursue further study of a temperature monitoring system under magnetic hyperthermia treatment.


1 D. Kouzoudis et al., frontiers in Materials 8, 638019 (2021)
2 A. Shikano et al., T. Magn. Soc. Jpn. (Special Issues) 6, 100-104 (2022).
3 M. Sekino et al., Scientific Reports 8, 1195 (2018)
4 K. Taruno et al., J. Surg. Oncol. 120, 1391 (2019)


Transcript English (automatic)

Next from MMM 2022

Anomalous Valley Hall Effect in A type Antiferromagnetic Van der Waals Heterostructures
technical paper

Anomalous Valley Hall Effect in A type Antiferromagnetic Van der Waals Heterostructures

MMM 2022

Hongxin Yang
Yingmei Zhu and 1 other author

07 November 2022

Stay up to date with the latest Underline news!

Select topic of interest (you can select more than one)


  • All Lectures
  • For Librarians
  • Resource Center
  • Free Trial
Underline Science, Inc.
1216 Broadway, 2nd Floor, New York, NY 10001, USA

© 2023 Underline - All rights reserved