Lecture image placeholder

Premium content

Access to this content requires a subscription. You must be a premium user to view this content.

Monthly subscription - $9.99Pay per view - $4.99Access through your institutionLogin with Underline account
Need help?
Contact us
Lecture placeholder background


MMM 2022

November 07, 2022

Minneapolis, United States

Concentration dependent Oscillation of Specific Loss Power in Magnetic Nanofluid Hyperthermia

Magnetic nanofluid hyperthermia (MNFH) using colloidal superparamagnetic nanoparticles (SPNPs) has attracted considerable attentions as a potential treatment modality in cancer clinics due to its clinical efficacies including deep tissue penetration of AC magnetic heat induction power (specific loss power (SLP)) and prominently low side effect 1,2. Accordingly, plenty of research activities were conducted to design and develop high-performance SPNPs with sufficient SLP for destroying tumors by cancer apoptosis or necrosis 3,4. However, magnetic dipole coupling between the colloidal SPNPs depending on the concentration was regarded as a critical role in characterizing SLP in MNFH. Although the concentration-dependent SLP change behavior has been intensively investigated, the physical mechanism is still poorly understood, and some contradictory results have been recently reported 5,6.
In this work, interparticle distance (dc-c)-dependent magnetic dipole coupling energy induced in nanofluids and their physical contribution to the SLP change behavior were investigated and analyzed by measuring the intrinsic/extrinsic magnetic parameters of nanofluids as a function of concentration. We first found and reported that the SLP of SPNP MNFH agent shows strong concentration-dependent oscillation behavior. According to the experimentally and theoretically analyzed results, the energy competition among the magnetic dipole interaction energy (Edip), magnetic potential energy (Ep), and exchange energy (Eex), was revealed as the main physical reason for the oscillation behavior shown in Fig. 1. The empirically demonstrated new finding and physically established model on the concentration-dependent SLP oscillation behavior is expected to provide biomedically crucial information in determining the critical dose of an agent for clinically safe and highly efficient MNFH in cancer clinics.

Next from MMM 2022

Heatrapy 2.0: a two dimensional upgrade for computing dynamic heat transfer processes in Python involving non conventional phenomena

Heatrapy 2.0: a two dimensional upgrade for computing dynamic heat transfer processes in Python involving non conventional phenomena

MMM 2022

Daniel Silva
Daniel Silva

07 November 2022

Stay up to date with the latest Underline news!

Select topic of interest (you can select more than one)


  • All Lectures
  • For Librarians
  • Resource Center
  • Free Trial
Underline Science, Inc.
1216 Broadway, 2nd Floor, New York, NY 10001, USA

© 2023 Underline - All rights reserved