France

Discover the art of creating extraordinary science at SEB’s Annual Conference at Le Corum Conference Center     in Montpellier, France from 5 to  8 July 2022.

SEB’s Annual Conference is celebrated for creating the perfect composition of research, new discoveries and collaborative connections. Be creative and innovative by exchanging ideas and knowledge with masters of biology from all over the world.

2022 will find over 1500 experimental biologists from across the globe converging on the third-largest French city near the Mediterranean coast and the fastest-growing city in the country over the past 25 years.
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Please register for the conference by clicking on this link:

https://www.sebiology.org/events/seb-annual-conference-2022/registration.html

The site will be open for registered participants closer to the event.

SEB Annual Conference 2022

2022 will find over 1500 experimental biologists from across the globe converging on the third-largest French city near the Mediterranean coast and the fastest-growing city in the country over the past 25 years - Montpellier, France

Mitochondria possess a genome, a vestige of their bacterial ancestor. Over the course of evolution, most of the genes of the ancestor have been lost or transferred to the nucleus. In humans, the mtDNA is limited to 37 genes, with little room for evolutionary novelties. This is radically different from bacterial genomes, which are much larger, and in which we can find genes inside other genes. These sequences are called alternatives open reading frames or altORFs, and they have key functions. By ignoring altORFS, have we underestimated the coding potential of the mitogenome? We found a downstream alternative ATG initiation codon in the +3 reading frame of the human mitochondrial nd4 gene. This newly characterized mitochondrial altORF encodes a 99-amino acids long polypeptide termed MTALTND4 with a completely different amino acid sequence from ND4. MTALTND4 is localized in mitochondria and is also found in the plasma, and it impacts mitochondrial physiology. These findings indicate that mitochondrial genes in humans (and other species) have gone unnoticed. This calls into question the evolution of the mitochondrial genome as well as the selection pressures exerted on the mitochondria and the mechanisms allowing the translation of these alternative proteins. We anticipate that more studies on the alternative mitochondrial proteome will expedite the discovery of new mitochondrial genes with key biological roles.

The underestimated protein coding potential of the mitochondrial genome

technical paper

Flight muscle mitochondria are seasonally plastic in a migratory songbird

No Bones About It: Soft Tissue Dynamics during Mammalian Mastication

Jaw-tongue coordination during chewing in Pigs

Integration across anatomy and physiology is the basis for understanding feeding behaviour in vertebrates

Skeleton in the skin? Teeth in the skin!

The physiological effects of experimental evolution of aerobic exercise performance in bank voles

Insights to genetic associations of life-history and metabolic rate via large-effect loci in Atlantic salmon

Macroevolutionary patterns in metabolism and development

Variation in field metabolic rates of wild marine fishes: thermal, ontogenetic, phylogenetic and macroecological drivers.

The vacuole - cytoskeleton connection: a handle to regulate growth

https://assets.underline.io/transcript/38747/subtitle/ba1b6cdcd649f6beae4ddcd2e9f05640.vtt

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The underestimated protein coding potential of the mitochondrial genome

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Flight muscle mitochondria are seasonally plastic in a migratory songbird

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