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Large Language Models (LLMs) are increasingly adopted as conversational assistants in genomics, where they are mainly used to reason over biological knowledge, annotations, and analysis outputs through natural language interfaces. However, existing benchmarks either focus on specialized DNA models trained for sequence prediction or evaluate biological knowledge using text-only questions, leaving the behavior of general-purpose LLMs when directly exposed to raw genome sequences underexplored. We introduce GenomeQA, a benchmark designed to provide a controlled evaluation setting for general-purpose LLMs on sequence-based genome inference tasks. GenomeQA comprises 5,200 samples drawn from multiple biological databases, with sequence lengths ranging from 6 to 1,000 base pairs (bp), spanning six task families: Enhancer and Promoter Identification, Splice Site Identification, Taxonomic Classification, Histone Mark Prediction, Transcription Factor Binding Site Prediction, and TF Motif Prediction. Across six frontier LLMs, we find that models often outperform random baselines, particularly on tasks driven by local sequence cues such as GC content and short motifs, while performance degrades on tasks that require more indirect or multi-step inference over sequence patterns. GenomeQA establishes a diagnostic benchmark for studying and improving the use of general-purpose LLMs on raw genomic sequences.

ACL 2026

GenomeQA: Benchmarking General Large Language Models for Genome Sequence Understanding

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### THE CONFERENCE WE KNOW AND WE WANT.
**COLING**, the International Conference on Computational Linguistics, is one of the premier conferences for the natural language processing and computational linguistics.

First established in 1965, the biennial COLING conference is held in diverse parts of the globe and attracts participants from both top-ranked research centers and emerging countries. Today, the most important developments in our field are taking place not only in universities and academic research institutes but also in industrial research departments including tech-startups. COLING provides opportunities for all these communities to showcase their exciting discovery.

In fall of 2022, COLING will be held in Gyeongju in a hybrid format. All participants can either present at the venue site or join virtually. As more people get vaccinated, we are happy to provide safer environments for our colleagues. We believe that COLING 2022 will be one of the conferences, free from the pandemic. The hybrid format gives presenters and sponsors a valuable opportunity to promote their companies in both an online and in-person venue. For the first time in a long time, customers can interact with their sponsor's products first-hand. The online venue, too, gives sponsors the chance to network with those unable to attend the in-person session.

The hybrid format ultimately lends itself to greater exposure for our sponsors: COLING2022 will let you reach more potential partners and customers than ever before!

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COLING 2022

COLING, the International Conference on Computational Linguistics, is one of the premier conferences for the natural language processing and computational linguistics.

poster

It is my great pleasure and honor to welcome you to the 64th Annual Meeting of the Association for Computational Linguistics (ACL 2026), held in San Diego, California, USA, July 2–7, 2026. ACL 2026 continues our fields tradition of excellence in scholarship, innovation, and inclusivity, and I am deeply grateful to the many volunteers who have worked tirelessly to bring this event to life.

It is exciting to see the many developments in the field reflected at our conference, such as the advancement of large language models (born out of our community) into many application directions. This is not without challenges, partly due to unsolved problems, and partly due to misuse of the technology. All this is reflected well at ACL 2026. The conference also reflects that the field is not only about advancing technology, but also the science of fundamentally understanding language and how it is use by many different speaker communities. 
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The 64th Annual Meeting of the Association for Computational Linguistics (ACL 2026) will take place in San Diego, California, from July 2 - 7, 2026.

Mixture-of-Experts (MoE) models rely on an external router to assign tokens to experts. This design inherently separates the routing decision from each expert's internal capabilities, leading to suboptimal performance. In this work, we address this limitation with Union-of-Experts (UoE), an MoE variant that performs "expert-autonomous routing''. The core mechanism of UoE is to pre-designate a minute fraction of neurons within each expert as "routing neurons''. Experts autonomously select relevant tokens by comparing the activation intensity of these neurons, aligning routing decisions with each expert’s functional profile. To prevent the waste of activations from unselected experts' routing neurons, we aggregate all routing neuron outputs and sum them into the final layer output. This aggregation acts as a novel virtual shared expert whose parameters are distributed across the individual experts, and improves overall parameter efficiency. We pre-train UoE models with up to 3B parameters, demonstrating that they outperform traditional MoEs with matched efficiency. Furthermore, our analysis of the routing neurons provides valuable insights into expert-autonomous selection and the broader routing mechanisms of MoE models.

Union-of-Experts: Neurons in Mixture-of-Experts are Secretly Routers

While large language models (LLMs) have substantially improved Text-to-SQL generation, a pronounced gap remains between AI systems and human experts on challenging benchmarks such as BIRD-SQL. We argue this gap stems largely from the prevailing single-pass paradigm, which lacks the iterative reasoning, schema exploration, and error-correction behaviors that humans naturally employ. To address this limitation, we introduce SQL-Trail, a multi-turn reinforcement learning (RL) agentic framework for Text-to-SQL. Rather than producing a query in one shot, SQL-Trail interacts with the database environment and uses execution feedback to iteratively refine its predictions. Our approach centers on two key ideas: (i) an adaptive turn-budget allocation mechanism that scales the agent’s interaction depth to match question difficulty, and (ii) a composite reward panel that jointly incentivizes SQL correctness and efficient exploration. Across benchmarks, SQL-Trail sets a new state of the art and delivers strong data efficiency—up to **18×** higher than prior single-pass RL state-of-the-art methods. Notably, our 7B and 14B models outperform substantially larger proprietary systems by **5%** on average, underscoring the effectiveness of interactive, agentic workflows for robust Text-to-SQL generation.

SQL-Trail: Multi-Turn Reinforcement Learning with Interleaved Feedback for Text-to-SQL

Despite the rapid advancement of LLMs, their performance on linguistically and culturally diverse minority languages within a unified national context remains underexplored. We present CMiLBench, a collection of hierarchical multitask benchmarks designed to translate theoretical notions of “diversity in unity” into practical evaluation for three representative Chinese minority languages: Tibetan, Mongolian, and Uyghur. CMiLBench comprises 24,663 instances across 5 difficulty levels and 17 tasks spanning foundational ability, cultural specificity, and safety alignment. We adopt existing dataset adaptation, minority knowledge construction, and high-resource benchmark translation to construct CMiLBench. We assess 14 state-of-the-art commercial and open-source LLMs with a hybrid framework that integrates automatic metrics and LLM-as-a-Judge scoring. The comparative experimental results reveal the gap between theoretical capability and practical utility. CMiLBench serves as a foundational and scalable evaluation resource to bridge the digital language divide and promote the informatization and intelligentization of low-resource Chinese minority languages.

Diversity in Unity, Theory in Practice: Hierarchical Multitask Benchmarks for Chinese Minority Languages

Large language model (LLM) agents are increasingly acting as human delegates in multi-agent environments, where a representative agent integrates diverse peer perspectives to make a final decision. Drawing inspiration from social psychology, we investigate how the reliability of this representative agent is undermined by the social context of its network. We define four key phenomena---social conformity, perceived expertise, dominant speaker effect, and rhetorical persuasion---and systematically manipulate the number of adversaries, relative intelligence, argument length, and argumentative styles. Our experiments demonstrate that the representative agent’s accuracy consistently declines as social pressure increases: larger adversarial groups, more capable peers, and longer arguments all lead to significant performance degradation. Furthermore, rhetorical strategies emphasizing credibility or logic can further sway the agent's judgment, depending on the context. These findings reveal that multi-agent systems are sensitive not only to individual reasoning but also to the social dynamics of their configuration, highlighting critical vulnerabilities in AI delegates that mirror the psychological biases observed in human group decision-making.

Social Dynamics as Critical Vulnerabilities that Undermine Objective Decision-Making in LLM Collectives

Developing culturally grounded multilingual AI systems remains challenging, particularly for low-resource languages. While synthetic data offers promise, its effectiveness in multilingual and multicultural contexts is underexplored. We investigate bottom-up synthetic data generation using large open-source LLMs (>= 235B parameters) grounded in language-specific Wikipedia content, complementing dominant top-down translation-based approaches from English. We introduce Updesh, a high-quality large-scale synthetic instruction-following dataset comprising 9.5M data points across 13 Indian languages and English, encompassing diverse reasoning and generative tasks emphasizing on enhancing long-context and multi-turn capabilities while improving alignment with Indian cultural contexts. Comprehensive evaluation using automated metrics and 10K human assessments confirms high data quality. Downstream evaluations performed by fine-tuning models on various datasets and assessing performance across 13 diverse multilingual datasets and model comparative evaluations, demonstrate that models trained on Updesh consistently obtain significant improvements on NLG tasks and remain competitive on NLU tasks. Improvements are most pronounced for low and medium-resource languages, effectively narrowing performance gaps with high-resource languages. Our findings provide empirical evidence that effective multilingual AI development requires multi-faceted, culturally grounded data curation strategies beyond translation-based approaches.

UPDESH: Synthesizing Grounded Instruction Tuning Data for 13 Indic Languages

Supervised Fine-Tuning (SFT) followed by Reinforcement Learning (RL) has emerged as the standard post-training paradigm for large language models (LLMs). However, the conventional SFT process, driven by Cross-Entropy (CE) loss, often induces mode collapse, where models over-concentrate on specific response patterns. This lack of distributional diversity severely restricts the exploration efficiency required for subsequent RL. While recent studies have attempted to improve SFT by replacing CE loss, aiming to preserve diversity or refine the update policy, they fail to adequately balance diversity and accuracy, thereby achieving sub-optimal performance after RL. To address the mode collapse problem, we propose SED-SFT, which adaptively encourages diversity based on the token exploration space. This framework introduces a selective entropy regularization term with a selective masking mechanism into the optimization objective. Extensive experiments across eight mathematical benchmarks demonstrate that SED-SFT significantly enhances generation diversity with a negligible computational overhead increase compared with CE loss, yielding average improvements of 2.06 and 1.20 points in subsequent RL performance over standard CE-based baselines on Llama-3.2-3B-Instruct and Qwen2.5-Math-7B-Instruct, respectively.

SED-SFT: Selectively Encouraging Diversity in Supervised Fine-Tuning

Embedding fusion has become a widely adopted technique for enhancing performance across various NLP tasks. While prior research suggests that different layers of language models encode distinct representations and that pooling strategies influence performance, there is a lack of systematic analysis regarding the empirical efficacy of these differences or the impact of combining embeddings from multiple models. This study provides a rigorous, empirical evaluation of layer-wise fusion strategies to determine their actual contribution to classification performance. Our findings reveal that the effectiveness of individual layers is more dependent on dataset characteristics than on the model architecture itself. Furthermore, we demonstrate that fusing embeddings from multiple models yields more robust and consistent representations across tasks, with the influence of any single model diminishing as the number of integrated models increases. Notably, experiments on low-resource datasets show that embedding fusion provides particularly significant gains when training data is scarce, highlighting its robustness and adaptability in data-constrained environments. We also analyze the trade-off between performance gains and computational overhead, and discuss which fusion configurations provide the best balance between stability and efficiency.

Beyond Single Representations: Multi-Model Embedding Fusion for Stable Text Classification

Large Language Models (LLMs) are increasingly applied in high-stakes domains such as finance, healthcare, and education, where reliable multi-turn interactions with users are essential. However, existing work on confidence estimation and calibration, a major approach to building trustworthy LLM systems, largely focuses on single-turn settings and overlooks the risks and potential of multi-turn conversations. In this work, we introduce the task of multi-turn calibration to reframe calibration from a static property into a dynamic challenge central to reliable multi-turn conversation, where calibrating model confidence at each turn conditioned on the conversation history is required. We first reveal the risks of this setting: using Expected Calibration Error at turn T (ECE@T), a new metric that tracks calibration dynamics over turns, we show that user feedback (e.g., persuasion) can degrade multi-turn calibration. To address this, we propose MTCal, which minimises ECE@T via a surrogate calibration target, and further leverage calibrated confidence in ConfChat, a decoding strategy that improves both factuality and consistency of the model response in multi-turn interactions. Extensive experiments demonstrate that MTCal achieves outstanding and consistent performance in multi-turn calibration, and ConfChat preserves and even enhances model performance in multi-turn interactions. Our results mark multi-turn calibration as one missing link for scaling LLM calibration toward safe, reliable, and real-world use. The code is available at: https://github.com/petezone/Multiturn-Calibration.

Confidence Should Be Calibrated More Than One Turn Deep

Large language models (LLMs) are fluent but often brittle when interpretation depends on external information (e.g., events or participant roles), as next-token prediction does not explicitly encode situation-level semantic constraints. FrameNet provides a structured account of semantics through its inventory of frames, roles, and relations. We present a scalable framework that injects frame-semantic knowledge into LLMs via LoRA, moving from fact-oriented prompting to principle-oriented supervision over the full FrameNet inventory. The supervision encodes semantic constraints through semantic types, sense-aware definitions, frame relations, and role-annotated examples. To test whether this knowledge generalizes beyond surface cues, we use Natural Language Inference (NLI) as a diagnostic task for event-level reasoning. Experiments on CONFER and SNLI show consistent gains over Meta-Llama-3.1-8B-Instruct in zero-shot and few-shot settings, especially for entailment and contradiction. Complementary semantic role labeling analyses further indicate improved sensitivity to frame, role, and span structure.

Frame-Semantic Knowledge Injection for Event-Level Inference in LLMs

Retrieval-augmented generation(RAG) systems depend on retrieval modules to supply grounding evidence for large language models. While hybrid approaches combining sparse and dense retrievers improve performance, most rely on fixed weights that ignore query-specific and corpus-specific variation. Similarly, query expansion has long been used to enrich recall, but its integration with original queries is usually static and can introduce noise. We present QuDAR, a dual-perspective adaptive retrieval framework that adapts along two perspectives: retriever type (sparse vs. dense) and query format (original vs.expanded). Leveraging margin-derived confidence (e.g., top-1--top-2 score gaps) and blind LLM-based relevance scoring, QuDAR dynamically assigns query-specific weights, fusing lexical specificity with semantic breadth while mitigating noise. QuDAR is lightweight, retriever-agnostic, and broadly applicable. Experiments show consistent gains over static baselines, improving overall retrieval quality and yielding more stable performance across queries.

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