United States

Interactive medical questioning is essential in clinical consultations, where physicians must actively gather necessary patient information. Yet existing medical Large Language Models (LLMs) predominantly follow a reactive paradigm, risking diagnostic errors by answering before seeking sufficient details. To bridge this gap, we propose ProMed, a reinforcement learning framework that transitions LLMs toward a proactive paradigm, enabling them to ask clinically valuable questions before decision-making. Central to ProMed is the Shapley Information Gain (SIG) reward, which quantifies a question&#39;s clinical utility as the amount of newly acquired information, while considering its contextual importance via Shapley values. We integrate SIG into a two-stage training pipeline: (1) SIG-Guided Model Initialization uses Monte Carlo Tree Search to construct high-reward interaction trajectories for supervision, and (2) SIG-Augmented Policy Optimization, with a novel SIG-guided Reward Distribution Mechanism that prioritizes informative questions for fine-grained optimization. Experiments on partial-information medical benchmarks show that ProMed significantly outperforms state-of-the-art methods by 6.29% on average and delivers a 54.45% gain over the reactive paradigm, and generalizes robustly to out-of-domain cases. Our codes are available at https://github.com/hxxding/ProMed.

ACL 2026

ProMed: Shapley Information Gain Guided Reinforcement Learning for Proactive Medical LLMs

Interactive medical questioning is essential in clinical consultations, where physicians must actively gather necessary patient information. Yet existing medical Large Language Models (LLMs) predominantly follow a reactive paradigm, risking diagnostic errors by answering before seeking sufficient details. To bridge this gap, we propose ProMed, a reinforcement learning framework that transitions LLMs toward a proactive paradigm, enabling them to ask clinically valuable questions before decision-making. Central to ProMed is the Shapley Information Gain (SIG) reward, which quantifies a question's clinical utility as the amount of newly acquired information, while considering its contextual importance via Shapley values. We integrate SIG into a two-stage training pipeline: (1) SIG-Guided Model Initialization uses Monte Carlo Tree Search to construct high-reward interaction trajectories for supervision, and (2) SIG-Augmented Policy Optimization, with a novel SIG-guided Reward Distribution Mechanism that prioritizes informative questions for fine-grained optimization. Experiments on partial-information medical benchmarks show that ProMed significantly outperforms state-of-the-art methods by 6.29% on average and delivers a 54.45% gain over the reactive paradigm, and generalizes robustly to out-of-domain cases. Our codes are available at https://github.com/hxxding/ProMed.

poster

It is my great pleasure and honor to welcome you to the 64th Annual Meeting of the Association for Computational Linguistics (ACL 2026), held in San Diego, California, USA, July 2–7, 2026. ACL 2026 continues our fields tradition of excellence in scholarship, innovation, and inclusivity, and I am deeply grateful to the many volunteers who have worked tirelessly to bring this event to life.

It is exciting to see the many developments in the field reflected at our conference, such as the advancement of large language models (born out of our community) into many application directions. This is not without challenges, partly due to unsolved problems, and partly due to misuse of the technology. All this is reflected well at ACL 2026. The conference also reflects that the field is not only about advancing technology, but also the science of fundamentally understanding language and how it is use by many different speaker communities. <br>
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Supervised Fine-Tuning (SFT) and Reinforcement Learning (RL) dominate the post-training landscape for mathematical reasoning, yet differ fundamentally in their reliance on expert trajectories. To understand the optimal way to harness these trajectories for maximizing performance, we propose the Plasticity-Ceiling Framework. This framework empirically grounds the post-training landscape by decomposing the ﬁnal performance ceiling into the foundational SFT performance and the subsequent RL plasticity (i.e., the maximum improvement via RL). Through extensive benchmarking, we establish the Sequential SFT-then-RL pipeline as the superior standard, overcoming the stability and premature convergence deﬁcits inherent in synchronized approaches. Furthermore, we derive precise scaling guidelines: (1) Transitioning to RL at the Stable or Mild Overﬁtting Regime of SFT maximizes the ﬁnal ceiling by securing a robust SFT foundation with substantial RL plasticity; (2) Refuting the “Less is More” hypothesis in SFT-then-RL scaling, we demonstrate that Data Scale determines the primary post-training potential, while Trajectory Difﬁculty acts as a performance multiplier; and (3) The Minimum Validation Loss of SFT serves as a reliable indicator for selecting the expert trajectories that maximize the ultimate performance ceiling. Our ﬁndings provide actionable guidelines for extracting maximum value from expert trajectories.

 Rethinking Expert Trajectory Utilization in LLM Post-training for Mathematical Reasoning

Competitive programming has become a rigorous benchmark for evaluating the reasoning and problem-solving capabilities of large language models (LLMs). The International Olympiad in Informatics (IOI) stands out as one of the most prestigious annual competitions in competitive programming and has become a key benchmark for comparing human and AI-level programming ability. While several proprietary models have been claimed to achieve gold medal-level performance at the IOI, often with undisclosed methods, achieving comparable results with open-weight models remains a significant challenge. In this paper, we present GenCluster, a scalable and reproducible test-time compute framework that attains IOI gold-level performance using open-weight models. It combines large-scale generation, behavioral clustering, ranking, and a round-robin submission strategy to efficiently explore diverse solution spaces under limited validation budgets. Our experiments show that the performance of our proposed approach scales consistently with available compute, narrowing the gap between open and closed systems. Notably, we will show that GenCluster can achieve a gold medal at IOI 2025 for the first time with an open-weight model gpt-oss-120b, setting a new benchmark for transparent and reproducible evaluation of reasoning in LLMs.

Scaling Test-Time Compute to Achieve IOI Gold Medal with Open-Weight Models

Robustness has become a critical attribute for the deployment of RAG systems in real-world applications. Existing research focuses on robustness to explicit noise (e.g., document semantics) but overlooks implicit noise (spurious features). Moreover, previous studies on spurious features in LLMs are limited to specific types (e.g., formats) and narrow scenarios (e.g., ICL). In this work, we identify and study spurious features in the RAG paradigm, a robustness issue caused by the sensitivity of LLMs to semantic-agnostic features. We then propose a novel framework,\textit{SURE}, to empirically quantify the robustness of RALMs against spurious features. Beyond providing a comprehensive taxonomy and metrics for evaluation, the framework’s data synthesis pipeline facilitates training-based strategies to improve robustness. Further analysis suggests that spurious features are a widespread and challenging problem in the field of RAG. Our code is available at https://anonymous.4open.science/r/RAG-SpuriousFeatures-62B3.

Quantifying and Improving the Robustness of Retrieval-Augmented Language Models Against Spurious Features in Grounding Data

Overlapping calendar invitations force busy professionals to repeatedly decide which meetings to attend, reschedule, or decline. We refer to this preference-driven decision process as calendar conflict resolution. Automating this decision process is crucial yet challenging. Scheduling logistics can drain hours, and human delegation often fails at scale, which motivates us to ask: Can we trust large language models (LLMs) or language agents to manage time? To enable a systematic study of this question, we introduce CalConflictBench, a benchmark for long-horizon calendar conflict resolution. In CalConflictBench, conflicts are presented to agents round-by-round over a calendar year, requiring them to infer and adapt to user preferences progressively. Our experiments show that current LLM agents perform poorly with high error rates, e.g., Qwen-3-30B-Think has an average error rate of 35%. To address this gap, we propose PEARL, a reinforcement-learning framework that (i) augments the language agent with an external preference memory that stores and updates inferred strategies (e.g., attendee priorities, topic importance, time/location preferences), and (ii) optimizes the agent with round-wise rewards that directly supervise decision correctness, ranking quality, and memory usage across rounds. Experiments on CalConflictBench show that PEARL achieves an error reduction rate of 0.76 and a 55% improvement in average error rate compared to the strongest baseline.

PEARL: Self-Evolving Assistant for Time Management with Reinforcement Learning

GraphRAG augments large language models with structured knowledge graphs, enabling graph-based context selection and a more integrated view of the knowledge space. However, recent work shows that GraphRAG exposes a new attack surface: corpus-level knowledge poisoning can inject spurious entities and relationships during graph construction, corrupting query-specific subgraphs and steering the generator toward incorrect answers. We propose Hop-wise Guard for GraphRAG (HoG-GRAG), a defense layer between retriever and generator that decomposes multi-hop questions into ordered subqueries, monitors hop-wise execution for poisoning-induced inconsistencies, and locally repairs the retrieved subgraph by pruning compromised entities and relationships and adding only minimal missing evidence. Experiments on multi-hop datasets and multiple GraphRAG configurations show that HoG-GRAG recovers a large fraction of the lost performance. The code is available at https://github.com/CyberScienceLab/HoG-GRAG.

Defense Against Knowledge Poisoning Attack on GraphRAG

Retrieval-augmented generation (RAG) has become a common practice in multimodal large language models (MLLM) to enhance factual grounding and reduce hallucination. Yet, its reliance on retrieval exposes MLLMs to knowledge poisoning attacks, in which adversaries deliberately inject malicious multimodal content into external knowledge bases to steer models toward generating incorrect or even harmful responses. We present MM-PoisonRAG, a framework to systematically study the vulnerability of multimodal RAG under knowledge poisoning. Specifically, we design two novel attack strategies: Localized Poisoning Attack (LPA), which implants targeted, query-specific multimodal misinformation to manipulate outputs toward attacker-controlled responses, and Globalized Poisoning Attack (GPA), which uses a single, untargeted adversarial injection to broadly corrupt reasoning and collapse generation quality across all queries. Extensive experiments on diverse tasks, multimodal RAG components, and attacker access levels reveal severe vulnerabilities: LPA achieves up to 56% attack success rate even under restricted access, and transfers effectively across four different retrievers without re-optimizing the adversaries. GPA completely disrupts model generation to 0% accuracy with just one poisoned content. Moreover, both LPA and GPA bypass existing defenses, underscoring the fragility of multimodal RAG and establishing MM-PoisonRAG as a foundation for future research on securing RAG frameworks against multimodal knowledge poisoning.

MM-PoisonRAG: Disrupting Multimodal RAG with Local and Global Knowledge Poisoning Attacks

Information-seeking is a core capability for AI agents, requiring them to gather and reason over tool-generated information across long trajectories. However, such multi-step information-seeking tasks remain challenging for agents backed by language models. While process reward models (PRMs) can guide agents by ranking candidate steps at test-time, existing PRMs, designed for short reasoning with binary judgment, cannot capture richer dimensions of information-seeking steps, such as tool interactions and reasoning over tool outputs, nor handle the rapidly growing context in long-horizon tasks. To address these limitations, we introduce PRInTS, a generative PRM trained with dual capabilities: (1) dense scoring based on the PRM’s reasoning across multiple step quality dimensions (e.g., interpretation of tool outputs, tool call informativeness) and (2) trajectory summarization that compresses the growing context while preserving essential information for step evaluation. Extensive evaluations across FRAMES, GAIA (levels 1-3), and WebWalkerQA (easy-hard) benchmarks on multiple models, with ablations, reveal that best-of-n sampling with PRInTS enhances information-seeking in open-source models as well as specialized agents, matching or surpassing frontier models with a much smaller backbone agent and outperforming other strong reward modeling baselines.

PRInTS: Reward Modeling for Long-Horizon Information Seeking

Cross-architecture GPU code transpilation is essential for unlocking low-level hardware portability, yet no scalable solution exists. We introduce CASS, the first dataset and model suite for source- and assembly-level GPU translation (CUDA ↔ HIP, SASS ↔ RDNA3). CASS contains 60k verified host-device code pairs, enabling learning-based translation across both ISA and runtime boundaries. We generate each sample using our automated pipeline that scrapes, translates, compiles, and aligns GPU programs across vendor stacks. Leveraging CASS, we train a suite of domain-specific translation models that achieve 88.2% accuracy on CUDA → HIP and 69.1% on SASS → RDNA3, outperforming commercial baselines including GPT-5.1, Claude-4.5, and Hipify by wide margins. Generated code matches native performance in 85% of cases, preserving both runtime and memory behavior. To support rigorous evaluation, we introduce CASS-Bench, a curated benchmark spanning 18 GPU domains with ground-truth execution. All data, models, and evaluation tools will be released as open source to support progress in GPU compiler tooling, binary compatibility, and LLM-guided code translation.

CASS: Nvidia to AMD Transpilation with Data, Models, and Benchmark

Linking FDA-approved medical devices to their underlying United States Patent and Trademark Office (USPTO) patents enables critical applications such as recall root-cause analysis, M\&A-driven IP discovery, and technology trajectory mapping. However, this cross-domain entity linking task remains unexplored due to severe **semantic gaps**: FDA documents focus on clinical outcomes, while patents describe technical mechanisms, yielding minimal lexical overlap. We formalize medical device-patent linking as a challenging cross-domain entity linking problem characterized by label scarcity and domain shifts. Using cardiovascular devices as a high-impact, representative domain featuring diverse technologies, high recall rates, and abundant disclosures, we construct a benchmark with 434 devices, 698K patents, and 585 high-fidelity expert-verified pairs. To address these challenges, we propose Bridge-MedDevKG, a coarse-to-fine framework that integrates (1) **MedDevOnto**, a domain-specific ontology that anchors device concepts via three-tier UMLS normalization; (2) **Multi-signal candidate generation** fusing company affiliation, semantic similarity, and ontology-weighted entity overlap; and (3) **Heterogeneous reranking** with multi-signal scoring and XGBoost classification on hard negatives. Our approach achieves a conservative lower-bound recall of 91.6\% on the gold standard with 50.9\% noise reduction, substantially outperforming LLM baselines under comparable evaluation. The resulting MedDevKG provides 6.8M high-confidence links, laying a scalable foundation for regulatory-IP integration across medical specialties.

From Regulatory Approvals to Patents: Cross-Domain Linking for Cardiovascular Device Traceability

The rapid advancement in large language models (LLMs) has demonstrated significant potential in End-to-End Software Development (E2ESD). However, existing E2ESD benchmarks are limited by coarse-grained requirement specifications and unreliable evaluation protocols, hindering a true understanding of current framework capabilities. To address these limitations, we present E2EDev, a novel benchmark grounded in the principles of Behavior-Driven Development (BDD) to assess whether the generated software meets user needs through mimicking real user interactions. E2EDev comprises (i) a fine-grained set of user requirements for each target software project (ii) multiple BDD test scenarios with corresponding Python step implementations for each requirement, and (iii) a fully automated testing pipeline built on the Behave framework. By evaluating various E2ESD frameworks and LLM backbones with E2EDev, our analysis reveals a persistent struggle to effectively solve these tasks, underscoring the critical need for more effective and cost-efficient E2ESD solutions. Our codebase and benchmark are available at https://github.com/SCUNLP/E2EDev.

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