Singapore

High-resolution computed tomography (CT) is essential for diagnosing hearing loss and planning interventions such as cochlear implantation, as it provides detailed visualization of inner-ear anatomy. This paper focuses on advancing AI-based analysis of inner-ear CT scans to support clinical decision-making. However, a major challenge lies in the scarcity of annotated data, which limits the applicability of conventional supervised learning techniques. To address this, we present the first publicly available Children&#39;s Inner Ear CT Dataset (CIED), comprising 722 CT scans labeled for structural anomaly detection, postoperative hearing outcome prediction, and anatomical segmentation. In addition, we explore the use of medical foundation models to improve generalization in data-scarce scenarios. Existing parameter-efficient adaptation methods often fall short in two ways: they lack a unified mechanism to adapt across diverse foundation model architectures and they are not specifically designed to incorporate domain expert knowledge of inner-ear anatomy and pathology. To overcome these limitations, we propose Domain Knowledge Guided Tuning (DKGT), a plug-and-play framework that introduces a unified adapter—Domain Knowledge Aggregator (DKA)—to inject radiomics-based anatomical features into foundation models via cross-attention. DKA supports various backbone types and preserves pretrained representations of foundation model while enabling multi-layer integration of expert knowledge. Extensive experiments across multiple tasks demonstrate that DKGT consistently outperforms state-of-the-art classification methods, achieving superior performance and generalizability on inner-ear CT analysis.

AAAI 2026

Tuning Medical Foundation Models for Inner Ear Temporal CT Analysis with Plug-and-play Domain Knowledge Aggregator

domain knowledge incorporation

inner ear ct analysis

parameter-efficient fine-tuning

You need to log in with the email address you registered with. Access credentials have been sent to your email. 

Please be sure to check your spam and other email folders if you do not see an email confirmation right away.

Please log in to explore this event.

If you see this page it means you are not logged in or registered.

If you feel like you see this message by mistake please make sure you are logged in with the email you registered with.

If you are not registered yet, you can do so [**here**](https://www.sebiology.org/events/seb-conference-prague-2024/registration2024.html). 

Please login or register

SEB Conference 2024

SEB’s Annual Conference is celebrated for creating the perfect composition of research, new discoveries and collaborative connections. Be creative and innovative by exchanging ideas and knowledge with masters of biology from all over the world.

High-resolution computed tomography (CT) is essential for diagnosing hearing loss and planning interventions such as cochlear implantation, as it provides detailed visualization of inner-ear anatomy. This paper focuses on advancing AI-based analysis of inner-ear CT scans to support clinical decision-making. However, a major challenge lies in the scarcity of annotated data, which limits the applicability of conventional supervised learning techniques. To address this, we present the first publicly available Children's Inner Ear CT Dataset (CIED), comprising 722 CT scans labeled for structural anomaly detection, postoperative hearing outcome prediction, and anatomical segmentation. In addition, we explore the use of medical foundation models to improve generalization in data-scarce scenarios. Existing parameter-efficient adaptation methods often fall short in two ways: they lack a unified mechanism to adapt across diverse foundation model architectures and they are not specifically designed to incorporate domain expert knowledge of inner-ear anatomy and pathology. To overcome these limitations, we propose Domain Knowledge Guided Tuning (DKGT), a plug-and-play framework that introduces a unified adapter—Domain Knowledge Aggregator (DKA)—to inject radiomics-based anatomical features into foundation models via cross-attention. DKA supports various backbone types and preserves pretrained representations of foundation model while enabling multi-layer integration of expert knowledge. Extensive experiments across multiple tasks demonstrate that DKGT consistently outperforms state-of-the-art classification methods, achieving superior performance and generalizability on inner-ear CT analysis.

poster

We are pleased to announce the Fortieth AAAI Conference on Artificial Intelligence (AAAI-26), which will be held in Singapore EXPO from January 20 to January 27, 2026.

The purpose of the AAAI conference series is to promote research in Artificial Intelligence (AI) and foster scientific exchange between researchers, practitioners, scientists, students, and engineers across the entirety of AI and its affiliated disciplines. AAAI-26 will feature technical paper presentations, special tracks, invited speakers, workshops, tutorials, poster sessions, senior member presentations, competitions, and exhibit programs, and a range of other activities to be announced.<br><br>

To access this event page, you need to log in with the **email address you registered with**. <br>Access credentials will be sent to your email from Underline -  subject line "Welcome to AAAI 2026". Please be sure to check your spam email folder if you do not see an email confirmation right away.

Please log in

To access this event page, you are required to register.
Please complete your registration to continue.

We recommend reading [**the registration information**](https://aaai.org/conference/aaai/aaai-26/registration/) first.

**Online Registration Form**: https://aaai.getregistered.net/conference-2026 

Registration Required

We are pleased to announce the Fortieth AAAI Conference on Artificial Intelligence (AAAI-26), which will be held in Singapore EXPO from January 20 to January 27, 2026.

Current methods for content safety in Large Language Models (LLMs), such as Supervised Fine-Tuning (SFT) and Reinforcement Learning from Human Feedback (RLHF), often rely on multi-stage training pipelines and lack fine-grained, post-deployment controllability. To address these limitations, we propose a unified co-training framework that efficiently integrates multiple safety behaviors: positive (lawful/prosocial), negative (unfiltered/risk-prone) and rejective (refusal-oriented/conservative) within a single SFT stage. Notably, each behavior is dynamically activated via a simple system-level instruction, or magic token, enabling stealthy and efficient behavioral switching at inference time. This flexibility supports diverse deployment scenarios, such as positive for safe user interaction, negative for internal red-teaming, and rejective for context-aware refusals triggered by upstream moderation signals. This co-training strategy induces a distinct Safety Alignment Margin in the output space, characterized by well-separated response distributions corresponding to each safety mode. The existence of this margin provides empirical evidence for the model's safety robustness and enables unprecedented fine-grained control. Experiments show that our method matches the safety alignment quality of SFT+DPO, with our 8B model notably surpassing DeepSeek-R1 (671B) in safety performance, while significantly reducing both training complexity and deployment costs. This work presents a scalable, efficient, and highly controllable solution for LLM content safety.

Efficient Switchable Safety Control in LLMs via Magic-Token-Guided Co-Training

Intelligent agents in real-world applications must adapt their behavior to changing contexts and user preferences. For example, planning a road trip requires considering both travel time and cost. Multi-objective reinforcement learning (MORL) provides a principled approach to navigate such trade-offs. However, most existing approaches require predefined preference weights during training and jointly optimize the model for all objectives. In this paper, we introduce TORA (Train Once, Realign Anytime), a novel framework that defers preference integration to inference time, enabling flexible adaptation to user preferences without retraining. TORA independently trains diffusion planning models for each objective and combines them at inference time using user-specified preferences to generate behavior aligned with desired trade-offs. Furthermore, new objectives can be added seamlessly by training additional models without modifying existing ones. Empirical evaluations on standard offline MORL benchmarks demonstrate that TORA achieves competitive and consistent performance compared to methods that require fixed preference weights.

TORA: Train Once, Realign Anytime for Offline Multi-Objective Reinforcement Learning

Alignment methods in moral domains seek to elicit moral preferences of human stakeholders and incorporate them into AI. This presupposes moral preferences as static targets, but such preferences often evolve over time. Proper alignment of AI to dynamic human preferences should ideally account for "legitimate" changes to moral reasoning, while ignoring changes related to attention deficits, cognitive biases, or other arbitrary factors. However, common AI alignment approaches largely neglect temporal changes in preferences, posing serious challenges to proper alignment, especially in high-stakes applications of AI, e.g., in healthcare domains, where misalignment can jeopardize the trustworthiness of the system and yield serious individual and societal harms. This work investigates the extent to which people’s moral preferences change over time, and the impact of such changes on AI alignment. Our study is grounded in the kidney allocation domain, where we elicit responses to pairwise comparisons of hypothetical kidney transplant patients from over 400 participants across 3-5 days. We find that, on average, participants change their response to the same scenario presented at different times around 6--20% of the time (exhibiting "response instability"). Additionally, we observe significant shifts in several participants’ retrofitted decision-making models over time (capturing "model instability"). The predictive performance of simple AI models decreases as a function of both response and model instability. Moreover, predictive performance diminishes over time, highlighting the importance of accounting for temporal changes in preferences during training. These findings raise fundamental normative and technical challenges relevant to AI alignment, highlighting the need to better understand the object of alignment (what to align to) when user preferences change significantly over time, including the different mechanisms underlying this change.

Moral Change or Noise? On Problems of Aligning AI with Temporally Unstable Human Feedback

Large language models are increasingly influencing human moral decisions, yet current approaches focus primarily on evaluating rather than actively steering their moral decisions. 
We formulate this as an out-of-distribution moral alignment problem, where LLM agents must learn to apply consistent moral reasoning frameworks to scenarios beyond their training distribution. 
We introduce Moral-Reason-QA, a novel dataset extending 680 human-annotated, high-ambiguity moral scenarios with framework-specific reasoning traces across utilitarian, deontological, and virtue ethics, enabling systematic evaluation of moral generalization in realistic decision contexts.
Our learning approach employs Group Relative Policy Optimization with composite rewards that simultaneously optimize decision alignment and framework-specific reasoning processes to facilitate learning of the underlying moral frameworks. 
Experimental results demonstrate successful generalization to unseen moral scenarios, with softmax-normalized alignment scores improving by +0.757 for utilitarian and +0.450 for deontological frameworks when tested on out-of-distribution evaluation sets. 
The experiments also reveal training challenges and promising directions that inform future research.
These findings establish that LLM agents can be systematically trained to internalize and apply specific moral frameworks to novel situations, providing a critical foundation for AI safety as language models become more integrated into human decision-making processes.
Code and data will be open-sourced.

MoralReason: Generalizable Moral Decision Alignment for LLM Agents Using Reasoning-Level Reinforcement Learning

Overestimation in evaluating large language models (LLMs) has become an increasing concern. Due to the contamination of public benchmarks or imbalanced model training, LLMs may achieve unreal evaluation results on public benchmarks, either intentionally or unintentionally, which leads to unfair comparisons among LLMs and undermines their realistic capability assessments. Existing benchmarks attempt to address these issues by keeping test cases permanently secret, mitigating contamination through human evaluation, or repeatedly collecting and constructing new samples. However, these approaches fail to ensure reproducibility, transparency, and high efficiency simultaneously. Moreover, the extent of overestimation in current LLMs remains unquantified. To address these issues, we propose ArxivRoll, a dynamic evaluation framework inspired by one-time pad encryption in cryptography. ArxivRoll comprises two key components: i) SCP (Sequencing, Cloze, and Prediction), an automated generator for private test cases, and ii) Rugged Scores (RS), metrics that measure the proportion of public benchmark contamination and training bias. Leveraging SCP, ArxivRoll constructs a new benchmark every six months using recent articles from ArXiv and employs them for one-time evaluations of LLM performance. Extensive experiments demonstrate the high quality of our benchmark, and we provide a systematic evaluation of current LLMs. The source code is available at https://github.com/liangzid/ArxivRoll/.

How Much Do Large Language Model Cheat on Evaluation? Benchmarking Overestimation Under the One-Time-Pad-Based Framework

The rapid advancement of text-to-image generative models has catalyzed widespread applications. However, persistent model biases continue to pose significant challenges to their ethical and effective deployment, often resulting in adverse outcomes across many use cases. Previous research has primarily addressed bias in narrowly defined scenarios, typically involving single-subject generation with limited contextual variability. Such simplified tasks fall short of serving as meaningful model evaluations in more complex real-world settings. For example, the prompt ``an assistant wearing a pink hat'' may reflect female-inclined biases associated with a pink hat. The neglected joint effects of the semantic binding in the prompts cause significant failures in current debiasing approaches. This work investigates **how bias manifests under semantic binding**, where contextual associations between objects and attributes influence generative outcomes. We demonstrate that the underlying bias distribution can be amplified based on these associations. To address this, we introduce a bias adherence score that quantifies how specific object-attribute bindings activate bias. Using this score, we develop a training-free context-bias control framework that decouples the underlying bias from the semantic bindings, improving over 10% biases in compositional generation tasks. Our analysis of bias scores across various attribute-object bindings and token decorrelation highlights a fundamental challenge: reducing bias without disrupting essential semantic relationships. These findings expose critical limitations in current debiasing approaches when applied to semantically bound contexts, underscoring the need to reassess prevailing bias mitigation strategies.

How Bias Binds: Measuring Hidden Associations for Bias Control in Text-to-Image Compositions

Refusal on harmful prompts is a key safety behaviour in instruction‑tuned large language models (LLMs), yet the internal causes of this behaviour remain poorly understood. We study two public instruction tuned models—Gemma‑2-2B‑IT and LLaMA‑3.1-8B‑IT using sparse autoencoders (SAEs) trained on residual‑stream activations. Given a harmful prompt, we search the SAE latent space for feature sets whose ablation flips the model from refusal to compliance, demonstrating causal influence and creating a jailbreak. Our search proceeds in three stages: 1. Refusal Direction - Finding a refusal mediating direction and collecting SAE features close to that direction, followed by 2. Greedy Filtering - to prune this set to obtain a minimal set and finally 3. Interaction Discovery - a factorization‑machine (FM) model that captures non‑linear interactions among the remaining active features and the minimal set. This pipeline yields a broad set of jailbreak-critical features, offering insight into the mechanistic basis of refusal. Moreover, we also find evidence of redundant features which remain dormant unless earlier features are suppressed. Our findings highlight the potential for fine-grained auditing and targeted intervention in safety behaviours by manipulating the interpretable latent space.

Beyond I’m Sorry, I Can’t: Dissecting Large-Language-Model Refusal

Reinforcement learning (RL) has recently become a powerful yet resource-intensive approach for post-training large language models (LLMs). Incorporating curriculum learning (CL) into RL has been shown to significantly improve training efficiency, particularly in reasoning tasks. However, existing CL methods face substantial challenges in multi-objective RL (MORL) settings, including: (1) difficulty in evaluating model capabilities online, (2) challenges in assessing sample importance under diverse objectives, and (3) inherent trade-offs between online training and offline inference in dynamically designing the curriculum. To address these issues, we propose a **M**ulti-**R**eward space guided **A**daptive **C**urriculum **L**earning framework (**MRACL**), which is the first to incorporate curriculum learning into multi-objective RL. MRACL first constructs a multi-dimensional reward space via offline inference to establish initial reward profiles for each training sample. During training, based on reward space, it estimates the evolving model capabilities by computing the centroid of the space and calculates the sample priority score through its capability distance, optimization direction and historical evolution, which enables adaptive selection of the most informative training samples at each step, independent of the specific RL algorithm. After each RL training iteration, the reward space is dynamically updated to reflect the model's evolving capabilities and the shifting distribution of sample priorities. Experiments on multi-objective alignment tasks demonstrate that MRACL achieves 1.62× faster convergence compared to state-of-the-art curriculum methods and 2.55× faster than non-curriculum methods. Furthermore, it consistently outperforms all baselines in both win rate and rule-based evaluation metrics. We further provide an in-depth analysis of the key factors contributing to MRACL's effectiveness, and summarize its advantages, applicable scenarios, and generalization across diverse experimental settings.

MRACL: Multi-Reward Space Guided Adaptive Curriculum Reinforcement Learning for LLMs

Large Language Models (LLMs) commonly rely on explicit refusal prefixes for safety, making them vulnerable to prefix injection attacks. We introduce HumorReject, a novel data-driven approach that reimagines LLM safety by decoupling it from refusal prefixes through humor as an indirect refusal strategy. Rather than explicitly rejecting harmful instructions, HumorReject responds with contextually appropriate humor that naturally defuses potentially dangerous requests. Our approach effectively addresses common "over-defense" issues while demonstrating superior robustness against various attack vectors. Our findings suggest that improvements in training data design can be as important as the alignment algorithm itself in achieving effective LLM safety. The code and dataset are available at https://github.com/wooozihui/HumorReject.

HumorReject: Decoupling LLM Safety from Refusal Prefix via a Little Humor

In recent years, recommendation systems have evolved from providing a single list of recommendations to offering a comprehensive suite of topic-focused services. To better accomplish this task, conversational recommendation systems (CRS) have progressed from basic retrieval-augmented LLM generation to agentic systems with advanced reasoning and self-correction capabilities. However, agentic systems come with notable response latency—a longstanding challenge for conversational recommendation systems. To balance the trade-off between handling complex queries and minimizing latency, we propose AdaptJobRec, the first conversational job recommendation system that leverages autonomous agent to integrate personalized recommendation algorithm tools. The system employs a user query complexity identification mechanism to minimize response latency. For straightforward queries, the agent directly selects the appropriate tool for rapid responses. For complex queries, the agent uses the memory processing module to filter chat history for relevant content, then passes the results to the intelligent task decomposition planner, and finally executes the tasks using personalized recommendation tools. Evaluation on Walmart’s real-world career recommendation scenarios demonstrates that AdaptJobRec reduces average response latency by up to 53.3\% compared to competitive baselines, while significantly improving recommendation accuracy.

Downloads

Next from AAAI 2026

Efficient Switchable Safety Control in LLMs via Magic-Token-Guided Co-Training

Similar lecture

Auditory tuning to conspecific acoustic signals in an Eocene katydid

Stay up to date with the latest Underline news!

PRESENTATIONS

CONFERENCES

COMPANY

RESOURCES

.css-70qvj9{display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;-webkit-align-items:center;-webkit-box-align:center;-ms-flex-align:center;align-items:center;}Downloads

Next from AAAI 2026

Efficient Switchable Safety Control in LLMs via Magic-Token-Guided Co-Training

Similar lecture

Auditory tuning to conspecific acoustic signals in an Eocene katydid

Stay up to date with the latest Underline news!

PRESENTATIONS

CONFERENCES

COMPANY

RESOURCES

Downloads