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Over the past years, memes have evolved from being exclusively a medium of humorous exchanges to one that allows users to express a range of emotions freely and easily. With the ever-growing utilization of memes in expressing depressive sentiments, we conduct a study on identifying depressive symptoms exhibited by memes shared by users of online social media platforms. We introduce RESTOREx as a vital resource for detecting depressive symptoms in memes on social media through the Large Language Model (LLM) generated and human-annotated explanations. We introduce MAMA-Memeia, a collaborative multi-agent multi-aspect discussion framework grounded in the clinical psychology method of Cognitive Analytic Therapy (CAT) Competencies. MAMA-Memeia improves upon the current state-of-the-art by 7.55% in macro-F1 and is established as the new benchmark compared to over 30 methods.