The latest advancements in scene relighting have been predominantly driven by inverse rendering with 3D Gaussian Splatting (3DGS). However, existing methods remain overly reliant on precise camera parameters under static illumination conditions, which is prohibitively expensive and even impractical in real-world scenarios. In this paper, we propose a novel learning from Unposed views under Varied illuminations Relightable 3D Gaussian Splatting (dubbed UV-RGS), to address this challenge by jointly optimizing camera poses, 3DGS representations, surface materials, and environment illuminations (i.e., unknown and varied lighting conditions in training) using only unposed views under varied lightings. Firstly, UV-RGS presents a viewpoint dividing strategy to group inputs into constituent units, enabling each unit can perform similar poses and illuminations. Next, for each unit, to get the constituent model, UV-RGS establishes incrementally pose learning module to estimate coarse camera parameters, which also enjoy a proxy-view refinement to alleviate the sparse view learning. Additionally, for all constituent unit models, we introduce a holistic model learning strategy that integrates progressive unit aggregation component and the 3DGS coupled with camera poses joint optimization, which realizes the scene high-fidelity perception by the physical-based rendering. Extensive experiments on both real-world and synthetic challenging datasets demonstrate the effectiveness of UV-RGS, achieving the state-of-the-art performance for scene inverse rendering by learning 3DGS from only unposed views under varied illuminations.