Detecting mirror regions in RGB videos is essential for scene understanding in applications such as scene reconstruction and robotic navigation. Existing video mirror detectors typically rely on cues like inside-outside mirror correspondences and 2D motion inconsistencies. However, these methods often yield noisy or incomplete predictions when confronted with complex real-world video scenes, especially in areas with occlusion or limited visual features and motions. We observe that human perceive and navigate 3D occluded environments with remarkable ease, owing to Motion-in-Depth (MiD) perception. MiD integrates information from visual appearance (image colors and textures), the way objects move around us in 3D space (3D motions), and their relative distance from us (depth) to determine whether something is approaching or receding and to support navigation. Motivated by this neuroscience mechanism, we introduce MiD-VMD, the first approach to explicitly model MiD for video mirror detection. MiD-VMD jointly utilizes contrastive 3D motion, depth, and image features through two novel modules based on a combinational QKV transformer architecture. The Motion-in-Depth Attention Learning (MiD-AL) module captures complementary relationships across these modalities with combinatorial attention and enforces a compact encoding to represent global 3D transformations, resulting in more accurate mirror detection and reduced motion artifacts. The Motion-in-Depth Boundary Detection (MiD-BD) module further sharpens mirror boundaries by leveraging cross-modal attention on 3D motion and depth features. Extensive experiments show that MiD-VMD outperforms current SOTAs. We will release our code.