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Long Chain-of-Thought (CoT) reasoning has shown great promise in complex reasoning tasks, but its application to medical decision-making presents unique challenges.
Unlike structured tasks relying on static verification frameworks, medical decision-making requires dynamic validation through longitudinal clinical outcomes, exhibiting temporal-causal dependencies that complicate the verification of reasoning processes. 
Therefore, we introduce a novel data construction framework specifically designed for medical decision-making.
First, the framework analyzes real-world clinical cases to construct comprehensive timelines of medical events and identify critical decision points, including examination, diagnosis, and treatment.
Subsequently, the framework employs a clinical causality-aware strategy to generate decision-making questions at the identified critical decision points, along with reasoning traces and corresponding answers.
Finally, information drawn from future nodes serves as clinical logic-constrained criteria to re-evaluate and refine the soundness and coherence of the generated reasoning and responses.
Building on this, we present OncoCoT, an oncologic decision-making dataset derived from clinical records from the past four years across eight common cancer types.
Furthermore, we distill a subset of OncoCoT into a dedicated benchmark, OncoEval, to facilitate systematic evaluation of clinical reasoning capabilities in LLMs.
Evaluation results show that existing state-of-the-art reasoning models, such as Deepseek-r1 and GPT-o3, exhibit limited capability in addressing clinical problems in OncoEval, revealing room for improvement.

AAAI 2026

OncoCoT: A Temporal-causal Chain-of-Thought Dataset for Oncologic Decision-Making

technical paper

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We are pleased to announce the Fortieth AAAI Conference on Artificial Intelligence (AAAI-26), which will be held in Singapore EXPO from January 20 to January 27, 2026.

Deep learning approaches to object detection have achieved reliable detection of specific object classes in images. However, extending a model’s detection capability to new object classes requires large amounts of annotated training data, which is costly and time-consuming to acquire, especially for long-tailed classes with insufficient representation in existing datasets. We compare four different methods of generating synthetic data to finetune object detection models on novel object categories, particularly when limited data is available in the form of object-centric data (multi-view images or 3D models). Our approaches are based on simple image processing techniques, 3D rendering, and image generation models, each varying in complexity and image realism. We assess the ability of models finetuned using synthetic data to generalize to novel object classes in real-world data, and we achieve significant performance boosts in our data-constrained experimental setting.

Object-Centric Data Synthesis for Category-level Object Detection (Student Abstract)

How should we quantify the value of each training example when datasets are large, heterogeneous, and geometrically structured? Classical *Data‑Shapley* answers in principle, but its $O(n!)$ complexity and point‑wise perspective are ill‑suited to modern scales. We propose Hierarchical Contrastive Data Valuation (HCDV), a three‑stage framework that (i) learns a contrastive, geometry‑preserving representation, (ii) organises the data into a balanced coarse‑to‑fine hierarchy of clusters, and (iii) assigns Shapley‑style pay‑offs to *coalitions* via local Monte‑Carlo games whose budgets are propagated downward. HCDV collapses the factorial burden to $O\\bigl(T\sum_{\ell}K_{\ell}\bigr)=O(TK_{\max}\log n)$, rewards examples that sharpen decision boundaries, and regularises outliers through curvature‑based smoothness. We prove that HCDV approximately satisfies the four Shapley axioms with surplus loss $O(\eta\log n)$, enjoys sub‑Gaussian coalition deviation $\tilde{O}(1/\sqrt{T})$, and incurs at most $k\varepsilon_\infty$ regret for top‑$k$ selection. Experiments on four benchmarks — tabular, vision, streaming, and a 45 M‑sample CTR task — plus the OpenDataVal suite show that HCDV lifts accuracy by up to +5 pp, slashes valuation time by up to **$100\times$**, and directly supports tasks such as augmentation filtering, low‑latency streaming updates, and fair marketplace payouts.

From Points to Coalitions: Hierarchical Contrastive Shapley Values for Prioritizing Data Samples

Recent advances in deep learning have enabled highly accurate six-degree-of-freedom (6DoF) object pose estimation, driving its widespread use in real-world applications such as robotics, augmented reality, virtual reality, and autonomous systems. However, backdoor attacks pose a major security risk to deep learning models. By injecting malicious triggers into training data, an attacker can cause a model to perform normally on benign inputs but behave incorrectly under specific conditions. While most research on backdoor attacks has focused on 2D vision tasks, their impact on 6DoF pose estimation remains largely unexplored. Furthermore, unlike traditional backdoors that only change the object class, backdoors in 6DoF estimation must manipulate other dimensions, such as intrinsic camera parameters, translation, and rotation. Therefore, two-dimensional backdoor attack methods are completely ineffective against 6DoF pose estimation networks. To address this issue, we propose a novel backdoor attack framework to expose vulnerabilities in 6DoF pose estimation. Our framework uses synthetic and real 3D objects of varying shapes as triggers and assigns target poses to induce controlled erroneous pose outputs while maintaining normal behavior on clean inputs. We evaluated this attack on multiple models (including PVNet, DenseFusion, and PoseDiffusion) and datasets (such as Linemod, YCB-Video, and CO3D). Experimental results demonstrate that our approach achieves extremely high attack success rates without compromising performance on legitimate tasks. Across various models and objects, the backdoored network achieves up to 100% ADD accuracy on clean data, while also achieving 100% attack success rate (ASR) under trigger conditions. The accuracy of controlled erroneous pose output is also extremely high,as the attack sample achieves 97.70% ADD-P. These results demonstrate that the backdoor can be reliably implanted and activated, achieving a high attack success rate under trigger conditions and with negligible impact on benign data. Furthermore, we employ a simple defense method to demonstrate that our attack framework is undefendable. These findings reveal a potentially serious and previously underexplored threat to modern 6DoF pose estimation systems.

6DAttack: Backdoor Attacks in the 6DoF Pose Estimation

This work proposes a grammar-based chunking strategy that segments input streams into semantically complete units by parsing dependency relations (e.g., noun phrase boundaries, verb-object structures) and punctuation features. The method ensures chunk coherence and minimizes semantic fragmentation.

Building on this mechanism, we present SASST (Syntax-Aware Simultaneous Translation), an end-to-end framework integrating frozen Whisper encoder and decoder-only LLM. The unified architecture dynamically outputs translation tokens or <WAIT> symbols to jointly optimize translation timing and content, with target-side reordering addressing word-order divergence.

Experiments on CoVoST2 multilingual corpus (En to De/Zh/Ja) demonstrate significant translation quality improvements across languages, validating the effectiveness of syntactic structures in LLM-driven SimulST systems.

SASST: Leveraging Syntax-Aware Chunking and LLMs for Simultaneous Speech Translation

Conventional feedback, even when accompanied by brief explanations, rarely uncovers the hidden contradictions that trigger a learner's mistake. We bridge this gap with counterfactual question generation (CFQG): given a learner's answer, generate a follow-up question that deliberately contradicts it, compelling the learner to confront the underlying conflict. CFQG thus transforms assessment from passive scoring into an interactive and contradiction-centered dialogue that supports knowledge repair. To automate CFQG, we propose GapProbe, which probes the knowledge gap between a learner’s belief and curated facts through a knowledge graph (KG), then designs counterfactual questions (CFQs) that negate the belief. Identifying contradiction-aware triples, and more importantly, selecting those most likely to confuse the learner, are highly challenging in large-scale KGs. GapProbe tackles these challenges with an iterative ProConB cycle coupled with a schema-aware KGMap. By caching one- and multi-hop schema patterns of the KG, KGMap provides ``roadmap'' to guide LLMs jump to deep and contradiction-aware triples, beyond traditional step-wise graph traversal. We present the CFQG benchmark and corresponding metrics for evaluating how generated CFQs trigger, focus, and deepen learner reflection through explicit contradictions. 
Experiments on multiple datasets and LLMs show that GapProbe boosts LLM reasoning over KGs and generates follow-up questions that consistently promote deeper and more focused learner reflection.

Counterfactual Question Generation Uncovering Learner Contradictions

Predicting the distribution of future states in a stochastic system, known as belief propagation, is fundamental to reasoning under uncertainty. However, nonlinear dynamics often make analytical belief propagation intractable, requiring approximate methods. When the system model is unknown and must be learned from data, a key question arises: can we learn a model that (i) universally approximates general nonlinear stochastic dynamics, and (ii) supports analytical belief propagation? This paper establishes the theoretical foundations for a class of models that satisfy both properties. The proposed approach combines the expressiveness of normalizing flows for density estimation with the analytical tractability of Bernstein polynomials. Empirical results show the efficacy of our learned model over state-of-the art data-driven methods for belief propagation, especially for highly non-linear systems with non-additive, non-Gaussian noise.

Universal Learning of Stochastic Dynamics for Exact Belief Propagation Using Bernstein Normalizing Flows

Electric bicycles (e-bikes) have become the dominant mode of transportation in China’s urban instant delivery industry. However, many riders lack the experience to navigate complex traffic networks and diverse road conditions, leading to reduced delivery efficiency. To address this issue, we present Talking Trails, an e-bike delivery route planning system built upon an LLM-enhanced spatiotemporal trajectory model. Trained on millions of real-world delivery trajectories, fused with spatiotemporal and semantic data information, the model achieves a top-5 rider displacement prediction accuracy of 95\% and a route optimization rate of 82.1\%. In practice, we augment the core planner with an LLM-driven semantic layer that translates high-level user intent into executable tasks, then pair it with a battery-swap module that continuously validates route feasibility so the vehicle never runs out of charge mid-mission. Currently serving tens of thousands of riders, the system is projected to reduce average delivery mileage by 17\% and lower annual carbon emissions by 3978 tons. Overall, Talking Trails significantly improves delivery efficiency, offering a scalable and sustainable solution for instant delivery operations.

Talking Trails: LLM-Enhanced Spatiotemporal Trajectory Modeling for E-Bike Delivery Route Planning

Recent advances have focused on training high-performance spiking neural networks (SNNs) by leveraging surrogate gradient (SG) learning to estimate the derivatives of non-differentiable spiking activity. However, the distribution of neuronal membrane potentials varies across timesteps and progressively deviates toward both sides of the firing threshold during training. When threshold and SG remain fixed, this may lead to imbalanced spike firing rates and diminished gradient signals, which prevent SNNs from performing well. To address these issues, we propose a novel dual-stage synergistic learning algorithm that achieves forward adaptive thresholding and backward dynamic SG. In forward propagation, we adaptively adjust thresholds based on the distribution of membrane potential dynamics (MPD) at each timestep, which enriches neuronal diversity and effectively balances firing rates across layers. In backward propagation, drawing from the association between MPD and SG, we dynamically optimize the SG driven by thresholds to enhance gradient estimation through spatio-temporal alignment, effectively mitigating gradient information loss. Experimental results demonstrate that our method achieves significant performance improvements. Moreover, it allows neurons to fire stable proportions of spikes at each timestep and increases the proportion of neurons that obtain gradients in deeper layers. Code is available at Supplementary Materials.

DS-ATGO: Dual-Stage Synergistic Learning via Forward Adaptive Threshold and Backward Gradient Optimization for Spiking Neural Networks

Alignment is crucial for text-to-image (T2I) models to ensure that the generated images faithfully capture user intent while maintaining safety and fairness. Direct Preference Optimization (DPO) has emerged as a key alignment technique for large language models (LLMs), and its influence is now extending to T2I systems. This paper introduces **DPO-Kernels** for T2I models, a novel extension of DPO that enhances alignment across three key dimensions: *(i) Hybrid Loss*, which integrates embedding-based objectives with the traditional probability-based loss to improve optimization; *(ii) Kernelized Representations*, leveraging Radial Basis Function (RBF), Polynomial, and Wavelet kernels to enable richer feature transformations, ensuring better separation between safe and unsafe inputs; and *(iii) Divergence Selection*, expanding beyond DPO’s default Kullback–Leibler (KL) regularizer by incorporating alternative divergence measures such as Wasserstein and Rényi divergences to enhance stability and robustness in alignment training. We introduce **DETONATE**, the first large-scale benchmark of its kind, comprising approximately 100K curated image pairs, categorized as chosen and rejected. This benchmark encapsulates three critical axes of social bias and discrimination: *Race*, *Gender*, and *Disability*. The prompts are sourced from the hate speech datasets, while the images are generated using state-of-the-art T2I models, including Stable Diffusion 3.5 Large (SD-3.5), Stable Diffusion XL (SD-XL), and Midjourney. Furthermore, to evaluate alignment beyond surface metrics, we introduce the **Alignment Quality Index (AQI)**: a novel geometric measure that quantifies latent space separability of safe/unsafe image activations, revealing hidden model vulnerabilities. While alignment techniques often risk overfitting, we empirically demonstrate that DPO-Kernels preserve strong generalization bounds using the theory of Heavy-Tailed Self-Regularization (HT-SR). To foster further research, we publicly release DETONATE along with the complete codebase for DPO-Kernels.

DETONATE – A Benchmark for Text-to-Image Alignment and Kernelized Direct Preference Optimization

Artificial neural networks are popular for computer vision as they often give state-of-the-art
performance, but are difficult to interpret because of their complexity. This black box modeling is especially troubling when the application concerns human well-being such as in medical image analysis or autonomous driving. In this work, we propose a technique called routing path visualization for capsule networks, which reveals how much of each region in an image is routed to each capsule. In turn, this technique can be used to interpret the entity that a given capsule detects, and speculate how the network makes a prediction. We demonstrate our new visualization technique on several real world datasets. Experimental results suggest that routing path visualization can precisely localize the predicted class from an image, even though the capsule networks are trained using just images and their respective class labels, without additional information defining the location of the class in the image.

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Object-Centric Data Synthesis for Category-level Object Detection (Student Abstract)

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