Partial Label Learning (PLL) aims to train multi-class classifiers from examples where each instance is associated with a set of candidate labels, among which the ground-truth label is assumed to be included. While most existing studies assume that partial labels are both instance-independent and reliable, such assumptions often break down in real-world scenarios, where candidate sets may depend on instance-specific features and even exclude the ground-truth label. In this work, we investigate a more realistic setting termed Unreliable Instance-Dependent Partial Label Learning (UIDPLL). To address the challenges in UIDPLL, we propose a novel framework named Neighborhood-guided Label Augmentation and Pruning (NLAP). NLAP exploits the structural consistency among neighboring instances to progressively refine candidate label sets and integrates classifier feedback to disambiguate labels during training. This progressive mechanism improves classification performance by tackling ambiguity caused by noise and instance dependency in partial labels. Furthermore, we provide theoretical guarantees for the proposed NLAP framework, demonstrating that label ambiguity can be effectively reduced through appropriate refinement and pruning procedures. Extensive experiments on both benchmark and real-world datasets demonstrate the robustness and effectiveness of the proposed method.