The homogeneity and heterogeneity across modalities are critical factors that influence multimodal fusion. In Multimodal Sentiment Analysis (MSA), the inherent textual information within the audio modality induces cross-modality homogeneity with the text modality. Conversely, the mutual independence between text and vision modalities results in their cross-modal heterogeneity. Although existing disentangle-based methods achieve notable performance gains by separating modality features into distinct subspaces, they overlook the characteristics of cross-modality heterogeneity and homogeneity among different modalities. To this end, we propose a novel Modality-aware Disentangle and Fusion (MDF) framework to investigate the role of core modality features. Specifically, we first use text as the anchor to disentangle the audio modality and extract its unique modality-specific features, thereby establishing cross-modal heterogeneity among text, audio, and vision. We then introduce a Cross-Modality Heterogeneity Enhancement (CHE) module to refine these features, further reinforcing their heterogeneous characteristics. Finally, a Modality Adaptive Weighting (MAW) module is employed to dynamically assign weights to the text, sound, and vision modalities based on their potential contributions to sentiment prediction, achieving a more effective multimodal representation for MSA. Experimental evaluations on different benchmarks demonstrate MDF's superiority, with extensive ablation studies confirming its effectiveness.