Underwater Image Enhancement (UIE) focuses on improving visual quality from various underwater scenes. Existing methods simplistically treat various degradations as homogeneous, disregarding their intrinsic connections and causing models to blindly learn, resulting in conflicting optimization goals and visual distortions. To address above limitations, we propose a Conditional Prompt Learning via Degradation Perception (CPLDP) model, which employs conditional prompt as degradation perception priors and guides underwater image enhancement. Specifically, we show that the natural language prompts not only promote distinguishing different degraded images, but also aid in exploring more details with semantic information. Therefore, the proposed method generates five key degradation prompts (green/blue/green-blue color casts, uneven illumination and blurriness) with conditional prompt learning. Subsequently, considering the intrinsic relationships among different degradations, we employ degradation perceptions as priors and fine-tune the learning strategy to enhance underwater images. During training, an adaptive loss function with multi-degradations is designed, allowing it to effectively handle the task conflicts among multiple underwater degradations. Additionally, we conduct a human visual-based underwater dataset with various degradation types by subjective statistics. Extensive experiments on both full-reference and no-reference datasets demonstrate that our CPLDP can achieve better visual results and outperform state-of-the-art UIE methods across various degradation scenarios.