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A simultaneous enhancement of accuracy and diversity of predictions remains a challenge in ambiguous medical image segmentation (AMIS) due to the inherent trade-offs. While truncated diffusion probabilistic models (TDPMs) hold strong potential with a paradigm optimization, existing TDPMs suffer from entangled accuracy and diversity of predictions with insufficient fidelity and plausibility. To address the aforementioned challenges, we propose Ambiguity-aware Truncated Flow Matching (ATFM), which introduces a novel inference paradigm and dedicated model components. Firstly, we propose Data-Hierarchical Inference, a redefinition of AMIS-specific inference paradigm, which enhances accuracy and diversity at data-distribution and data-sample level, respectively, for an effective disentanglement. Secondly, Gaussian Truncation Representation (GTR) is introduced to enhance both fidelity of predictions and reliability of truncation distribution, by explicitly modeling it as a Gaussian distribution at $T_{\text{trunc}}$ instead of using sampling-based approximations. Thirdly, Segmentation Flow Matching (SFM) is proposed to enhance the plausibility of diverse predictions by extending semantic-aware flow transformation in Flow Matching (FM). Comprehensive evaluations on LIDC and ISIC3 datasets demonstrate that ATFM outperforms SOTA methods and simultaneously achieves a more efficient inference. ATFM improves GED and HM-IoU by up to 12% and 7.3% compared to advanced methods.

AAAI 2026

Ambiguity-aware Truncated Flow Matching for Ambiguous Medical Image Segmentation

technical paper

We are pleased to announce the Fortieth AAAI Conference on Artificial Intelligence (AAAI-26), which will be held in Singapore EXPO from January 20 to January 27, 2026.

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We are pleased to announce the Fortieth AAAI Conference on Artificial Intelligence (AAAI-26), which will be held in Singapore EXPO from January 20 to January 27, 2026.

Continual test-time adaptation (CTTA) enables online model adjustment under dynamic distribution shifts in real-world environments. However, most existing CTTA frameworks adopt fixed model architectures, lacking the structural flexibility required for deployment across heterogeneous edge devices with varying computational capacities. To address this, we propose an elastic framework for edge CTTA that performs resource-aware dynamic model search based on a pre-trained binary Supernet. This enables architectural flexibility by generating personalized models tailored to the resource constraints of different edge devices. Considering the evolving distribution of unlabeled data on edge devices during deployment, we introduce a pluggable lightweight fine-tuning mechanism. By inserting low-rank adapters into the frozen binary backbone, the model enables continual self-supervised adaptation with minimal computational overhead. In addition, we propose a structure-aware knowledge reflux mechanism that transfers the adaptation experience from fine-tuned edge models back into the Supernet. By distilling knowledge into structurally aligned Supernet paths, future architecture search is improved without requiring retraining. Experiments on multiple benchmarks validate that our method achieves state-of-the-art performance while significantly reducing resource consumption, with re-searched models after knowledge reflux showing further improvements.

Towards Robust Edge Model Adaptation via Elastic Architecture Search

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Parametric Pareto Set Learning for Expensive Multi-Objective Optimization

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