The presence of Per- and Polyfluoroalkyl Substances (PFAS) in food has become an increasing concern due to their persistence and bioaccumulation. As regulations tighten with decreasing action limits, the need for a harmonized and accurate method for PFAS determination is critical. Shellfish, as bottom feeders, are particularly susceptible to PFAS contamination from water and sediment. However, their high lipid content presents analytical challenges, and PFAS solvent extraction is inherently difficult due to contamination risks and the low concentrations at which these compounds occur. Traditional extraction methods are often manual, time-consuming, and inefficient. This study evaluates the EDGE PFAS™ system, an automated solvent extraction system, for extracting PFAS from shellfish. This method provides a streamlined process with efficient extraction, minimal sample handling, and high recovery rates with excellent reproducibility. The EDGE PFAS™ system offers a rapid, simple, and effective solution for PFAS testing in shellfish, supporting regulatory compliance and food safety efforts.