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Non-targeted methods have been gaining ground in recent decades, especially with the tremendous development of high-resolution mass spectrometry. The challenges for non-targeted methods are becoming increasingly necessary as there are limited guidelines to regulate and harmonize the methods worldwide. AOAC-Europe and have been signed a Memorandum of understanding for this sector. Two years ago, a series of Webinars on "Trends & Challenges for Non-Targeted Methods" have been started. As a result of this webinars a joint working group was set up with the aim of providing guidelines for the harmonization of non-targeted methods, mainly based on Mass Spectrometry. So far, the starting working group was now split into five subgroups dealing with food, authenticity, environmental/water, packaging and metabolomic testing. As an initial step the five groups are summarizing definitions and workflows for non-target testing. Based on the theses results a harmonized wording and where possible a harmonized workflow incl. validation should be created. The aim of this presentation is to present especially the result of the packing (food contact material area). The current status of initiation of common parameters as well harmonized criteria for reporting Screening (NIAS) results is presented. The focus of this harmonisation activity is on descriptive physico-chemical parameter, which allow the reader of such Screening reports to find out easily, if it worthwhile to compare results or are the test results achieved based on different assumptions. Currently the focus is only on the results but not on comparability, which lead to massive problems in understanding.
