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Diffusion models for garment-centric human generation from text or image prompts have garnered emerging attention for their great application potential. However, existing methods often face a dilemma: lightweight approaches, such as adapters, can result in inconsistent textures; while finetune-based methods involve high training costs and struggle to maintain the generalization capabilities of pretrained diffusion models, limiting their performance across diverse scenarios. To address these challenges, we propose DreamFit, which incorporates a lightweight Anything-Dressing Encoder specifically tailored for the garment-centric human generation. DreamFit has three key advantages: (1) Lightweight training: with the proposed adaptive attention and LoRA modules, DreamFit significantly minimizes the model complexity to 83.4M trainable parameters. (2)Anything-Dressing: Our model generalizes surprisingly well to a wide range of (non-)garments, creative styles, and prompt instructions, consistently delivering high-quality results across diverse scenarios. (3) Plug-and-play: DreamFit is engineered for smooth integration with any community control plugins for diffusion models, ensuring easy compatibility and minimizing adoption barriers. To further enhance generation quality, DreamFit leverages pretrained large multi-modal models (LMMs) to enrich the prompt with fine-grained descriptions of the garment, thereby reducing the prompt gap between training and inference. We conduct comprehensive experiments both on $768 \times 512$ high-resolution benchmarks and in-the-wild images. DreamFit surpasses all existing methods, highlighting its state-of-the-art capabilities of garment-centric human generation.