Thailand

Healthcare providers spend a significant amount of time reading and synthesizing electronic health records (EHRs), negatively impacting patient outcomes and causing provider burnout. Traditional supervised machine learning approaches using large language models (LLMs) to summarize clinical text have struggled due to hallucinations and lack of relevant training data. Here, we present a novel, simplified solution for the &quot;Discharge Me!&quot; shared task. Our approach mimics human clinical workflow, using pre-trained LLMs to answer specific questions and summarize the answers obtained from discharge summaries and other EHR sections. This method (i) avoids hallucinations through hybrid-RAG/zero-shot contextualized prompting; (ii) requires no extensive training or fine-tuning; and (iii) is adaptable to various clinical tasks.

ACL 2024

Roux-lette at &quot;Discharge Me!&quot;: Reducing EHR Chart Burden with a Simple, Scalable, Clinician-Driven AI Approach

free-text clinical notes

electronic health care records

llms

bionlp

Healthcare providers spend a significant amount of time reading and synthesizing electronic health records (EHRs), negatively impacting patient outcomes and causing provider burnout. Traditional supervised machine learning approaches using large language models (LLMs) to summarize clinical text have struggled due to hallucinations and lack of relevant training data. Here, we present a novel, simplified solution for the "Discharge Me!" shared task. Our approach mimics human clinical workflow, using pre-trained LLMs to answer specific questions and summarize the answers obtained from discharge summaries and other EHR sections. This method (i) avoids hallucinations through hybrid-RAG/zero-shot contextualized prompting; (ii) requires no extensive training or fine-tuning; and (iii) is adaptable to various clinical tasks.

Roux-lette at "Discharge Me!": Reducing EHR Chart Burden with a Simple, Scalable, Clinician-Driven AI Approach

workshop paper

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The 62nd Annual Meeting of the Association for Computational Linguistics (ACL 2024) will take place in Bangkok, Thailand from August 11th to 16th, 2024. More information will be announced soon.

This paper presents the approach of the iHealth-Chile-1 team for the shared task of Large-Scale Radiology Report Generation at the BioNLP workshop, 
inspired by progress in large multimodal models for processing images and text. In this work, we leverage LLaVA, a Visual-Language Model (VLM), composed of a vision-encoder, a vision-language connector or adapter, and a large language model able to process text and visual embeddings. We achieve our best result by enriching the input prompt of LLaVA with the text output of a simpler report generation model. With this enriched-prompt technique, we improve our results in 4 of 5 metrics (BLEU-4, Rouge-L, BertScore and F1-RadGraph,), only doing in-context learning. Moreover, we provide details about different architecture settings, fine-tuning strategies, and dataset configurations.

iHealth-Chile-1 at RRG24: In-context Learning and Finetuning of a Large Multimodal Model for Radiology Report Generation

In this work, we propose our top-ranking (2nd place) pipeline for the generation of discharge summary subsections as a part of the BioNLP 2024 Shared Task 2: "Discharge Me!". We evaluate both encoder-decoder and state-of-the-art decoder-only language models on the generation of two key sections of the discharge summary. To evaluate the ability of NLP methods to further alleviate the documentation burden on physicians, we also design a novel pipeline to generate the brief hospital course directly from structured information found in the EHR. Finally, we evaluate a constrained beam search approach to inject external knowledge about relevant patient problems into the text generation process. We find that a BioBART model fine-tuned on a larger fraction of the data without constrained beam search outperforms all other models.

Yale at "Discharge Me!": Evaluating Constrained Generation of Discharge Summaries with Unstructured and Structured Information

This paper presents our proposed approach to the Discharge Me! shared task, collocated with the 23th Workshop on Biomedical Natural Language Processing (BioNLP). In this work, we develop an LLM-based framework for solving the Discharge Summary Documentation (DSD) task, i.e., generating the two critical target sections `Brief Hospital Course' and `Discharge Instructions' in the discharge summary. By streamlining the recent instruction-finetuning process on LLMs, we explore several prompting strategies for optimally adapting LLMs to specific generation task of DSD. Experimental results show that providing a clear output structure, complimented by a set of comprehensive Chain-of-Thoughts (CoT) questions, effectively improves the model's reasoning capability, and thereby, enhancing the structural correctness and faithfulness of clinical information in the generated text. Source code is available at: https://anonymous.4open.science/r/Discharge_LLM-A233

IgnitionInnovators at "Discharge Me!": Chain-of-Thought Instruction Finetuning Large Language Models for Discharge Summaries

This paper presents the approaches of the iHealth-Chile-3 and iHealth-Chile-2 teams for the shared task of Large-Scale Radiology Report Generation at the BioNLP workshop. Inspired by prior work on template-based report generation, both teams focused on exploring various template-based strategies, using predictions from multi-label image classifiers as input.
Our best approach achieved a modest F1-RadGraph score of 19.42 on the findings hidden test set, ranking 7th on the leaderboard. Notably, we consistently observed a discrepancy between our classification metrics and the F1-CheXbert metric reported on the leaderboard, which always showed lower scores. This suggests that the F1-CheXbert metric may be missing some of the labels mentioned by the templates.

iHealth-Chile-3&2 at RRG24: Template Based Report Generation

This paper introduces a radiology-focused visual language model designed to generate radiology reports from chest X-rays. Building on previous findings that large language models can acquire multimodal capabilities when aligned with pretrained vision encoders, we demonstrate similar potential with chest X-ray images. The model combines an image encoder (CLIP) with a fine-tuned large language model (LLM) based on the Vicuna-7B architecture. The training process involves a two-stage approach: initial alignment of chest X-ray features with the LLM, followed by fine-tuning for radiology report generation. The study highlights the importance of generating both FINDINGS and IMPRESSIONS sections in radiology reports and evaluates the model's performance using various metrics, achieving notable accuracy in generating high-quality medical reports. The research also addresses the need for domain-specific fine-tuning to capture the intricate details necessary for accurate medical interpretations and reports.

Gla-AI4BioMed at RRG24: Visual Instruction-tuned Adaptation for Radiology Report Generation

Radiology report generation (RRG) aims to create free-text radiology reports from clinical imaging. Our solution employs a lightweight multimodal language model (MLLM) enhanced with a two-stage post-processing strategy, utilizing a Large Language Model (LLM) to boost diagnostic accuracy and ensure patient safety. We introduce the "First, Do No Harm" SafetyNet, which incorporates Xraydar, an advanced X-ray classification model, to cross-verify the model outputs and specifically address false negatives from the MLLM. This comprehensive approach combines the efficiency of lightweight models with the robustness of thorough post-processing techniques, offering a reliable solution for radiology report generation. Our system achieved fourth place on the F1-Radgraph metric for findings generation in the Radiology Report Generation Shared Task (RRG24).

SICAR at RRG2024: GPU Poor's Guide to Radiology Report Generation

Lay summarization is essential but challenging, as it simplifies scientific information for non-experts and keeps them updated with the latest scientific knowledge. In our participation in the Shared Task: Lay Summarization of Biomedical Research Articles @ BioNLP Workshop (Goldsack et al., 2024), ACL 2024, we conducted a comprehensive evaluation on abstractive summarization of biomedical literature using Large Language Models (LLMs) and assessed the performance using ten metrics across three categories: relevance, readability, and factuality, using eLife and PLOS datasets provided by the organizers. We developed a two-stage framework for lay summarization of biomedical scientific articles. In the first stage, we generated summaries using BART and PEGASUS LLMs by fine-tuning them on the given datasets. In the second stage, we combined the generated summaries and input them to BioBART, and then fine-tuned it on the same datasets. Our findings show that combining general and domain-specific LLMs enhances performance.

BioLay_AK_SS at BioLaySumm: Domain Adaptation by Two-Stage Fine-Tuning of Large Language Models used for Biomedical Lay Summary Generation

This paper details the efforts of the WisPerMed team in the BioLaySumm2024 Shared Task on automatic lay summarization in the biomedical domain, aimed at making scientific publications accessible to non-specialists. Large language models (LLMs), specifically the BioMistral and Llama3 models, were fine-tuned and employed to create lay summaries from complex scientific texts. The summarization performance was enhanced through various approaches, including instruction tuning, few-shot learning, and prompt variations tailored to incorporate specific context information. The experiments demonstrated that fine-tuning generally led to the best performance across most evaluated metrics. Few-shot learning notably improved the models' ability to generate relevant and factually accurate texts, particularly when using a well-crafted prompt. Additionally, a Dynamic Expert Selection (DES) mechanism to optimize the selection of text outputs based on readability and factuality metrics was developed. Out of 54 participants, the WisPerMed team reached the 4th place, measured by readability, factuality, and relevance. Determined by the overall score, our approach improved upon the baseline by approx. 5.5 percentage points and was only approx. 1.5 percentage points behind the first place.

WisPerMed at BioLaySumm: Adapting Autoregressive Large Language Models for Lay Summarization of Scientific Articles

This article presents our submission to the Bio-
LaySumm 2024 shared task: Lay Summarization
of Biomedical Research Articles. The objective
of this task is to generate summaries
that are simplified in a concise and less technical
way, in order to facilitate comprehension
by non-experts users. A pre-trained BioBART
model was employed to fine-tune the articles
from the two journals, thereby generating two
models, one for each journal. The submission
achieved the 12th best ranking in the task, attaining
a meritorious first place in the Relevance
ROUGE-1 metric.

HULAT-UC3M at BiolaySumm: Adaptation of BioBART and Longformer models to summarizing biomedical documents

Lay summarization of biomedical research articles is a challenging problem due to their use of technical terms and background knowledge requirements, despite the potential benefits of these research articles to the public. We worked on this problem as participating in BioLaySumm 2024. We experimented with various fine-tuning approaches to generate better lay summaries for biomedical research articles. After several experiments, we built a LoRA model with unsupervised fine-tuning based on the abstracts of the given articles, followed by a post-processing unit to take off repeated sentences. Our model was ranked 3rd overall in the BioLaySumm 2024 leaderboard. We analyzed the different approaches we experimented with and suggested several ideas to improve our model further.

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Roux-lette at "Discharge Me!": Reducing EHR Chart Burden with a Simple, Scalable, Clinician-Driven AI Approach

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iHealth-Chile-1 at RRG24: In-context Learning and Finetuning of a Large Multimodal Model for Radiology Report Generation

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